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. 2024 May;47(1):98-102.

Analysis of cases with co-infection of COVID-19 and pulmonary aspergillosis

Hui Zheng Hu  1 , Li Bo Wu  1 , Qian Liu  1 , Bin Yan Wu  1 , Yu Wang  2 , Rui Ying Wang  1
Affiliations
  • PMID: 38700889
Free article

Analysis of cases with co-infection of COVID-19 and pulmonary aspergillosis

Hui Zheng Hu et al. New Microbiol. 2024 May.
Free article

Abstract

The objective of this study was to investigate the risk factors and diagnosis measure of COVID-19-associated pulmonary aspergillosis (CAPA). This study included 201 COVID-19 patients from December 1, 2022, to January 31, 2023; 7 (3.5%) were diagnosed with CAPA. The main risk factors were age, MV, ICU admission and COPD, and the presence of comorbidities such as ARDS and hypoproteinemia in COVID-19 patients, more susceptible to Aspergillus infection. In addition to specimen culture in the lower respiratory tract, the 1,3-β-D-glucan antigen test can serve as an important screening indicator for early CAPA diagnosis in non-granulocytopenia patients.

Keywords: CAPA; COVID-19; diagnosis; infections; risk factors.

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