The 1+Million Genomes Minimal Dataset for Cancer

Michela Riba¹, Cinzia Sala¹, Aedin C Culhane², Åsmund Flobak^{3

4

5}, Attila Patocs^{6

7

8}, Kjetil Boye⁹, Karla Plevova^{10

11

12}, Šárka Pospíšilová^{10

11

12}, Giorgia Gandolfi¹, Marco J Morelli¹, Gabriele Bucci¹, Anders Edsjö^{13

14}, Ulrik Lassen¹⁵, Fátima Al-Shahrour¹⁶, Nuria Lopez-Bigas¹⁷, Randi Hovland¹⁸, Edwin Cuppen^{19

20}, Alfonso Valencia¹⁷, Helene A Poirel²¹, Richard Rosenquist^{22

23}, Serena Scollen²⁴, Juan Arenas Marquez²⁴, Jeroen Belien²⁵, Arcangela De Nicolo¹, Ruggero De Maria^{26

27}, David Torrents¹⁷, Giovanni Tonon^{28

29

30}

Affiliations

¹ Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.
² Limerick Digital Cancer Research Centre, Health Research Institute, School of Medicine, University of Limerick, Limerick, Ireland.
³ Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
⁴ The Cancer Clinic, St. Olav's University Hospital, Trondheim, Norway.
⁵ Department of Biotechnology and Nanomedicine, SINTEF Industry, Trondheim, Norway.
⁶ Department of Molecular Genetics and the National Tumour Biology Laboratory, National Institute of Oncology, Budapest, Hungary.
⁷ Department of Oncology Biobank, National Institute of Oncology, Budapest, Hungary.
⁸ Hereditary Tumours Research Group, Hungarian Academy of Sciences, Semmelweis University, Budapest, Hungary.
⁹ Department of Oncology, Oslo University Hospital, Oslo, Norway.
¹⁰ Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.
¹¹ Department of Internal Medicine - Hematology and Oncology, Faculty of Medicine, Masaryk University and University Hospital, Brno, Czech Republic.
¹² Department of Medical Genetics and Genomics, University Hospital and Faculty of Medicine, Brno, Czech Republic.
¹³ Department of Clinical Genetics, Pathology and Molecular Diagnostics, Office for Medical Services, Region Skåne, Lund, Sweden.
¹⁴ Division of Pathology, Department of Clinical Sciences, Lund University, Lund, Sweden.
¹⁵ Department of Oncology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
¹⁶ Bioinformatics Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
¹⁷ Institución Catalana de Investigación y Estudios Avanzados (ICREA), Barcelona, Spain.
¹⁸ Section of Cancer Genomics Haukeland University Hospital, Bergen, Norway.
¹⁹ Center for Molecular Medicine, Oncode Institute, University Medical Center Utrecht, Utrecht, the Netherlands.
²⁰ Hartwig Medical Foundation, Amsterdam, the Netherlands.
²¹ Cancer Centre, Sciensano, Brussels, Belgium.
²² Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
²³ Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden.
²⁴ ELIXIR Hub, Wellcome Genome Campus, Hinxton, Cambridge, UK.
²⁵ Department of Pathology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
²⁶ Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.
²⁷ Fondazione Policlinico Universitario 'A. Gemelli' - Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
²⁸ Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy. tonon.giovanni@hsr.it.
²⁹ Functional Genomics of Cancer Unit, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy. tonon.giovanni@hsr.it.
³⁰ Vita-Salute San Raffaele University, Milan, Italy. tonon.giovanni@hsr.it.

PMID: 38702538
DOI: 10.1038/s41588-024-01721-x

The 1+Million Genomes Minimal Dataset for Cancer

Michela Riba et al. Nat Genet. 2024 May.

. 2024 May;56(5):733-736.

doi: 10.1038/s41588-024-01721-x.

Authors

Affiliations

¹ Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.
² Limerick Digital Cancer Research Centre, Health Research Institute, School of Medicine, University of Limerick, Limerick, Ireland.
³ Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
⁴ The Cancer Clinic, St. Olav's University Hospital, Trondheim, Norway.
⁵ Department of Biotechnology and Nanomedicine, SINTEF Industry, Trondheim, Norway.
⁶ Department of Molecular Genetics and the National Tumour Biology Laboratory, National Institute of Oncology, Budapest, Hungary.
⁷ Department of Oncology Biobank, National Institute of Oncology, Budapest, Hungary.
⁸ Hereditary Tumours Research Group, Hungarian Academy of Sciences, Semmelweis University, Budapest, Hungary.
⁹ Department of Oncology, Oslo University Hospital, Oslo, Norway.
¹⁰ Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.
¹¹ Department of Internal Medicine - Hematology and Oncology, Faculty of Medicine, Masaryk University and University Hospital, Brno, Czech Republic.
¹² Department of Medical Genetics and Genomics, University Hospital and Faculty of Medicine, Brno, Czech Republic.
¹³ Department of Clinical Genetics, Pathology and Molecular Diagnostics, Office for Medical Services, Region Skåne, Lund, Sweden.
¹⁴ Division of Pathology, Department of Clinical Sciences, Lund University, Lund, Sweden.
¹⁵ Department of Oncology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
¹⁶ Bioinformatics Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
¹⁷ Institución Catalana de Investigación y Estudios Avanzados (ICREA), Barcelona, Spain.
¹⁸ Section of Cancer Genomics Haukeland University Hospital, Bergen, Norway.
¹⁹ Center for Molecular Medicine, Oncode Institute, University Medical Center Utrecht, Utrecht, the Netherlands.
²⁰ Hartwig Medical Foundation, Amsterdam, the Netherlands.
²¹ Cancer Centre, Sciensano, Brussels, Belgium.
²² Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
²³ Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden.
²⁴ ELIXIR Hub, Wellcome Genome Campus, Hinxton, Cambridge, UK.
²⁵ Department of Pathology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
²⁶ Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.
²⁷ Fondazione Policlinico Universitario 'A. Gemelli' - Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
²⁸ Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy. tonon.giovanni@hsr.it.
²⁹ Functional Genomics of Cancer Unit, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy. tonon.giovanni@hsr.it.
³⁰ Vita-Salute San Raffaele University, Milan, Italy. tonon.giovanni@hsr.it.

PMID: 38702538
DOI: 10.1038/s41588-024-01721-x

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References

1. Mardis, E. R. Nat. Cancer 2, 1263–1264 (2021). - DOI - PubMed
1. Jiang, P. et al. Nat. Rev. Cancer 22, 625–639 (2022). - DOI - PubMed - PMC
1. Sweeney, S. M. et al. Cancer Res. 83, 1175–1182 (2023). - DOI - PubMed - PMC
1. The Clinical Cancer Genome Task Team of the Global Alliance for Genomics and Health. N. Engl. J. Med. 376, 2006–2009 (2017). - DOI
1. Casaletto, J., Bernier, A., McDougall, R. & Cline, M. S. Annu. Rev. Genom. Hum. Genet. 24, 347–368 (2023). - DOI

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The 1+Million Genomes Minimal Dataset for Cancer

Affiliations

The 1+Million Genomes Minimal Dataset for Cancer

Authors

Affiliations

References

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

Medical