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Review
. 2024 Oct;16(5):1866-1874.
doi: 10.1007/s12602-024-10274-8. Epub 2024 May 4.

Potential Applications of Blautia wexlerae in the Regulation of Host Metabolism

Wen Rui #  1 , Xiaoqian Li #  1 , Lijun Wang  2 , Xuna Tang  3 , Jingpeng Yang  4
Affiliations
Review

Potential Applications of Blautia wexlerae in the Regulation of Host Metabolism

Wen Rui et al. Probiotics Antimicrob Proteins. 2024 Oct.

Abstract

Blautia wexlerae (B. wexlerae) is a strong candidate with the potential to become a next-generation probiotics (NGPs) and has recently been shown for the first time to exhibit potential in modulating host metabolic levels and alleviating metabolic diseases. However, the factors affecting the change in abundance of B. wexlerae and the pattern of its abundance change in the associated indications remain to be further investigated. Here, we summarize information from published studies related to B. wexlerae; analyze the effects of food source factors such as prebiotics, probiotics, low protein foods, polyphenols, vitamins, and other factors on the abundance of B. wexlerae; and explore the patterns of changes in the abundance of B. wexlerae in metabolic diseases, neurological diseases, and other diseases. At the same time, the development potential of B. wexlerae was evaluated in the direction of functional foods and special medical foods.

Keywords: Blautia wexlerae; Functional foods; Metabolic diseases; Next-generation probiotics (NGPs); Special medical foods.

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