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Multicenter Study
. 2024 Jun;26(6):1153-1165.
doi: 10.1111/codi.17015. Epub 2024 May 5.

Long-term restoration of bowel continuity after rectal cancer resection and the influence of surgical technique: A nationwide cross-sectional study

Sanne-Marije J A Hazen  1   2   3 , Eline G M van Geffen  1   2   3 , Tania C Sluckin  1   2   3 , Geerard L Beets  4   5 , Henricus J Belgers  6 , Wernard A A Borstlap  7 , Esther C J Consten  8   9 , Jan-Willem T Dekker  10 , Roel Hompes  2   7 , Jurriaan B Tuynman  1   2   3 , Henderik L van Westreenen  11 , Johannes H W de Wilt  12 , Pieter J Tanis  2   3   7   13 , Miranda Kusters  1   2   3 ; Dutch Snapshot Research Group
Collaborators, Affiliations
Multicenter Study

Long-term restoration of bowel continuity after rectal cancer resection and the influence of surgical technique: A nationwide cross-sectional study

Sanne-Marije J A Hazen et al. Colorectal Dis. 2024 Jun.

Abstract

Aim: Literature on nationwide long-term permanent stoma rates after rectal cancer resection in the minimally invasive era is scarce. The aim of this population-based study was to provide more insight into the permanent stoma rate with interhospital variability (IHV) depending on surgical technique, with pelvic sepsis, unplanned reinterventions and readmissions as secondary outcomes.

Method: Patients who underwent open or minimally invasive resection of rectal cancer (lower border below the sigmoid take-off) in 67 Dutch centres in 2016 were included in this cross-sectional cohort study.

Results: Among 2530 patients, 1470 underwent a restorative resection (58%), 356 a Hartmann's procedure (14%, IHV 0%-42%) and 704 an abdominoperineal resection (28%, IHV 3%-60%). Median follow-up was 51 months. The overall permanent stoma rate at last follow-up was 50% (IHV 13%-79%) and the unintentional permanent stoma rate, permanent stoma after a restorative procedure or an unplanned Hartmann's procedure, was 11% (IHV 0%-29%). A total of 2165 patients (86%) underwent a minimally invasive resection: 1760 conventional (81%), 170 transanal (8%) and 235 robot-assisted (11%). An anastomosis was created in 59%, 80% and 66%, with corresponding unintentional permanent stoma rates of 12%, 24% and 14% (p = 0.001), respectively. When corrected for age, American Society of Anesthesiologists classification, cTNM, distance to the anorectal junction and neoadjuvant (chemo)radiotherapy, the minimally invasive technique was not associated with an unintended permanent stoma (p = 0.071) after a restorative procedure.

Conclusion: A remarkable IHV in the permanent stoma rate after rectal cancer resection was found. No beneficial influence of transanal or robot-assisted laparoscopy on the unintentional permanent stoma rate was found, although this might be caused by the surgical learning curve. A reduction in IHV and improving preoperative counselling for decision-making for restorative procedures are required.

Keywords: permanent stoma; rectal cancer; robot‐assisted laparoscopy; total mesorectal excision; transanal total mesorectal excision.

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