Elongated linear vessels simulating branching vessels and diffuse structureless orange areas as prominent dermoscopic features of diffuse flat facial and extrafacial granuloma faciale: A case series

doi:10.1111/ajd.14298

Case Reports

. 2024 Aug;65(5):467-471.

doi: 10.1111/ajd.14298. Epub 2024 May 5.

Elongated linear vessels simulating branching vessels and diffuse structureless orange areas as prominent dermoscopic features of diffuse flat facial and extrafacial granuloma faciale: A case series

Francesco Savoia¹, Matelda Medri¹, Ignazio Stanganelli^{1

2}, Silvia Zago³, Lucia Domeniconi³, Davide Melandri^{4

5}, Mauro Alaibac⁶, Jacopo Tartaglia⁶, Christian Ciolfi⁶, Andrea Sechi⁷

Affiliations

¹ Skin Cancer Unit, IRCCS Istituto Romagnolo per Lo Studio Dei Tumori (IRST) "Dino Amadori", Meldola, Italy.
² Dermatology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy.
³ Patologic Anatomy, AUSL Della Romagna, Santa Maria Delle Croci Hospital, Ravenna, Italy.
⁴ Dermatology Unit, Bufalini Hospital, Cesena, Italy.
⁵ Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.
⁶ Dermatology Unit, Department of Medicine (DIMED), University of Padua, Padova, Italy.
⁷ Dermatology Unit, San Bortolo Hospital, Vicenza, Italy.

PMID: 38706196
DOI: 10.1111/ajd.14298

Case Reports

Elongated linear vessels simulating branching vessels and diffuse structureless orange areas as prominent dermoscopic features of diffuse flat facial and extrafacial granuloma faciale: A case series

Francesco Savoia et al. Australas J Dermatol. 2024 Aug.

. 2024 Aug;65(5):467-471.

doi: 10.1111/ajd.14298. Epub 2024 May 5.

Authors

Francesco Savoia¹, Matelda Medri¹, Ignazio Stanganelli^{1

2}, Silvia Zago³, Lucia Domeniconi³, Davide Melandri^{4

5}, Mauro Alaibac⁶, Jacopo Tartaglia⁶, Christian Ciolfi⁶, Andrea Sechi⁷

Affiliations

¹ Skin Cancer Unit, IRCCS Istituto Romagnolo per Lo Studio Dei Tumori (IRST) "Dino Amadori", Meldola, Italy.
² Dermatology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy.
³ Patologic Anatomy, AUSL Della Romagna, Santa Maria Delle Croci Hospital, Ravenna, Italy.
⁴ Dermatology Unit, Bufalini Hospital, Cesena, Italy.
⁵ Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.
⁶ Dermatology Unit, Department of Medicine (DIMED), University of Padua, Padova, Italy.
⁷ Dermatology Unit, San Bortolo Hospital, Vicenza, Italy.

PMID: 38706196
DOI: 10.1111/ajd.14298

Abstract

Dermoscopy can be an important help for the diagnosis of skin cancers and inflammatory cutaneous diseases. The list of the dermoscopic features reported in granuloma faciale is wide and includes vascular and non-vascular features. We report here three cases of diffuse flat facial and extrafacial granuloma faciale that exhibited elongated linear vessels simulating branching vessels and diffuse structureless orange areas. The differential diagnosis between flat-type granuloma faciale, basal cell carcinoma and cutaneous sarcoidosis can be extremely difficult, making histology mandatory before any treatment.

Keywords: branching vessels; dermoscopy; granuloma faciale; orange.

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Cited by

Dermoscopy of Basal Cell Carcinoma Part 3: Differential Diagnosis, Treatment Monitoring and Novel Technologies.
Wojtowicz I, Żychowska M. Wojtowicz I, et al. Cancers (Basel). 2025 Mar 19;17(6):1025. doi: 10.3390/cancers17061025. Cancers (Basel). 2025. PMID: 40149358 Free PMC article. Review.

References

REFERENCES

1. Peris K, Fargnoli MC, Garbe C, Kaufmann R, Bastholt L, Seguin NB, et al. Diagnosis and treatment of basal cell carcinoma: European consensus‐based interdisciplinary guidelines. Eur J Cancer. 2019;118:10–34.
1. Bombonato C, Argenziano G, Lallas A, Moscarella E, Ragazzi M, Longo C. Orange color: a dermoscopic clue for the diagnosis of granulomatous skin diseases. J Am Acad Dermatol. 2015;72(Suppl 1):S60–S63.
1. Lallas A, Sidiropoulos T, Lefaki I, Tzellos T, Sotiriou E, Apalla Z. Photoletter to the editor: dermoscopy of granuloma faciale. J Dermatol Case Rep. 2012;6(2):59–60.
1. Teixeira DA, Estrozi B, Ianhez M. Granuloma faciale: a rare disease from a dermoscopy perspective. An Bras Dermatol. 2013;88(6 Suppl 1):97–100.
1. Caldarola G, Zalaudek I, Argenziano G, Bisceglia M, Pellicano R. Granuloma faciale: a case report on long‐term treatment with topical tacrolimus and dermoscopic aspects. Dermatol Ther. 2011;24(5):508–511.

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[1] Peris K, Fargnoli MC, Garbe C, Kaufmann R, Bastholt L, Seguin NB, et al. Diagnosis and treatment of basal cell carcinoma: European consensus‐based interdisciplinary guidelines. Eur J Cancer. 2019;118:10–34.

[2] Peris K, Fargnoli MC, Garbe C, Kaufmann R, Bastholt L, Seguin NB, et al. Diagnosis and treatment of basal cell carcinoma: European consensus‐based interdisciplinary guidelines. Eur J Cancer. 2019;118:10–34.

[3] Bombonato C, Argenziano G, Lallas A, Moscarella E, Ragazzi M, Longo C. Orange color: a dermoscopic clue for the diagnosis of granulomatous skin diseases. J Am Acad Dermatol. 2015;72(Suppl 1):S60–S63.

[4] Bombonato C, Argenziano G, Lallas A, Moscarella E, Ragazzi M, Longo C. Orange color: a dermoscopic clue for the diagnosis of granulomatous skin diseases. J Am Acad Dermatol. 2015;72(Suppl 1):S60–S63.

[5] Lallas A, Sidiropoulos T, Lefaki I, Tzellos T, Sotiriou E, Apalla Z. Photoletter to the editor: dermoscopy of granuloma faciale. J Dermatol Case Rep. 2012;6(2):59–60.

[6] Lallas A, Sidiropoulos T, Lefaki I, Tzellos T, Sotiriou E, Apalla Z. Photoletter to the editor: dermoscopy of granuloma faciale. J Dermatol Case Rep. 2012;6(2):59–60.

[7] Teixeira DA, Estrozi B, Ianhez M. Granuloma faciale: a rare disease from a dermoscopy perspective. An Bras Dermatol. 2013;88(6 Suppl 1):97–100.

[8] Teixeira DA, Estrozi B, Ianhez M. Granuloma faciale: a rare disease from a dermoscopy perspective. An Bras Dermatol. 2013;88(6 Suppl 1):97–100.

[9] Caldarola G, Zalaudek I, Argenziano G, Bisceglia M, Pellicano R. Granuloma faciale: a case report on long‐term treatment with topical tacrolimus and dermoscopic aspects. Dermatol Ther. 2011;24(5):508–511.

[10] Caldarola G, Zalaudek I, Argenziano G, Bisceglia M, Pellicano R. Granuloma faciale: a case report on long‐term treatment with topical tacrolimus and dermoscopic aspects. Dermatol Ther. 2011;24(5):508–511.

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Elongated linear vessels simulating branching vessels and diffuse structureless orange areas as prominent dermoscopic features of diffuse flat facial and extrafacial granuloma faciale: A case series

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Elongated linear vessels simulating branching vessels and diffuse structureless orange areas as prominent dermoscopic features of diffuse flat facial and extrafacial granuloma faciale: A case series

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