Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Apr;40(2):255-260.
doi: 10.1007/s12288-023-01707-5. Epub 2023 Oct 16.

Etiology of Mild and Moderate Anaemia Among Rural Adolescent Girls in India

Aakriti Gupta  1 , Harshpal Singh Sachdev  2 , Umesh Kapil  3 , Shyam Prakash  4 , Ravindra Mohan Pandey  5 , Priti Rishi Lal  1
Affiliations

Etiology of Mild and Moderate Anaemia Among Rural Adolescent Girls in India

Aakriti Gupta et al. Indian J Hematol Blood Transfus. 2024 Apr.

Abstract

A cluster randomized control trial study was conducted in Ballabgarh block of Faridabad District, Haryana, India. Baseline data of a total of 198 non-anemic and 202 anemic adolescent girls (12-19 years) was analyzed for hemoglobin and serum level of hepcidin, ferritin, folate acid, soluble transferrin receptor, vitamin B12 and CRP. Deficiency of iron (p < 0.001), folate (p < 0.01) and their mixed deficiency (p < 0.001) significantly increased with increasing severity of anaemia and contributed to 48.7% mild anaemia and 66.9% moderate anaemia. Anaemia of inflammation contributed to 16.2% of mild anaemia and 11.7% of moderate anaemia. More than one third of mild anaemia is caused by other causes. Current iron and folic acid program can alleviate around more than 2/3rd moderate anaemia and around half of mild anaemia among adolescent girls. Unknown causes of anaemia need further investigation.

Keywords: Anaemia; Folate; Hepcidin; Inflammation; Iron.

PubMed Disclaimer

Conflict of interest statement

Conflict of interestThe authors have no relevant financial or non-financial interests to disclose.

Similar articles

See all similar articles

References

    1. Abbafati C, Abbas KM, Abbasi-Kangevari M, et al. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the global burden of disease study 2019. The Lancet. 2020;396:1204–1222. doi: 10.1016/S0140-6736(20)30925-9. - DOI - PMC - PubMed
    1. Beard JL. Iron requirements in adolescent females. J Nutr. 2000;130:440S–442S. doi: 10.1093/jn/130.2.440S. - DOI - PubMed
    1. Jáuregui-Lobera I. Iron deficiency and cognitive functions. Neuropsychiatr Dis Treat. 2014;10:2087–2095. doi: 10.2147/NDT.S72491. - DOI - PMC - PubMed
    1. World Health Organization (2011) Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. https://apps.who.int/iris/bitstream/handle/10665/85839/WHO_NMH_NHD_MNM_1...
    1. World Health Organization . The global prevalence of anaemia in 2011. Geneva: World Health Organization; 2015.

LinkOut - more resources