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. 2024 Apr;40(2):255-260.
doi: 10.1007/s12288-023-01707-5. Epub 2023 Oct 16.

Etiology of Mild and Moderate Anaemia Among Rural Adolescent Girls in India

Aakriti Gupta  1 , Harshpal Singh Sachdev  2 , Umesh Kapil  3 , Shyam Prakash  4 , Ravindra Mohan Pandey  5 , Priti Rishi Lal  1
Affiliations

Etiology of Mild and Moderate Anaemia Among Rural Adolescent Girls in India

Aakriti Gupta et al. Indian J Hematol Blood Transfus. 2024 Apr.

Abstract

A cluster randomized control trial study was conducted in Ballabgarh block of Faridabad District, Haryana, India. Baseline data of a total of 198 non-anemic and 202 anemic adolescent girls (12-19 years) was analyzed for hemoglobin and serum level of hepcidin, ferritin, folate acid, soluble transferrin receptor, vitamin B12 and CRP. Deficiency of iron (p < 0.001), folate (p < 0.01) and their mixed deficiency (p < 0.001) significantly increased with increasing severity of anaemia and contributed to 48.7% mild anaemia and 66.9% moderate anaemia. Anaemia of inflammation contributed to 16.2% of mild anaemia and 11.7% of moderate anaemia. More than one third of mild anaemia is caused by other causes. Current iron and folic acid program can alleviate around more than 2/3rd moderate anaemia and around half of mild anaemia among adolescent girls. Unknown causes of anaemia need further investigation.

Keywords: Anaemia; Folate; Hepcidin; Inflammation; Iron.

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Conflict of interest statement

Conflict of interestThe authors have no relevant financial or non-financial interests to disclose.

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