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. 2024 Jun;49(3):233-246.
doi: 10.1007/s00059-024-05246-1. Epub 2024 May 6.

[Treatment with cardiac electronic implantable devices]

[Article in German]
Affiliations

[Treatment with cardiac electronic implantable devices]

[Article in German]
Jürgen Kuschyk et al. Herz. 2024 Jun.

Abstract

Cardiac device therapy provides not only treatment options for bradyarrhythmia but also advanced treatment for heart failure and preventive measures against sudden cardiac death. In heart failure treatment it enables synergistic reverse remodelling and reduces pharmacological side effects. Cardiac resynchronization therapy (CRT) has revolutionized the treatment of reduced left ventricular ejection fraction (LVEF) and left bundle branch block by decreasing the mortality and morbidity with improvement of the quality of life and resilience. Conduction system pacing (CSP) as an alternative method of physiological stimulation can improve heart function and reduce the risk of pacemaker-induced cardiomyopathy. Leadless pacers and subcutaneous/extravascular defibrillators offer less invasive options with lower complication rates. The prevention of infections through preoperative and postoperative strategies enhances the safety of these therapies.

Die kardiale Device-Therapie bietet neben der Behandlung bradykarder Rhythmusstörungen fortgeschrittene Therapien für die Herzinsuffizienz und präventive Maßnahmen gegen den plötzlichen Herztod. In der Herzinsuffizienztherapie ermöglicht sie im integrierten Ansatz ein synergistisches „reverse remodeling“ und reduziert pharmakologische Nebenwirkungen. Die kardiale Resynchronisierungstherapie (CRT) hat die Behandlung bei reduzierter linksventrikulärer Ejektionsfraktion (LVEF) und Linksschenkelblock durch Senkung von Mortalität und Morbidität sowie Verbesserung der Lebensqualität und Belastbarkeit revolutioniert. Conduction System Pacing (CSP) als alternatives Verfahren der physiologischen Stimulation kann die Herzfunktion verbessern und das Risiko für eine schrittmacherinduzierte Kardiomyopathie verringern. „Leadless pacer“ und subkutane/extravaskuläre Defibrillatoren bieten weniger invasive Optionen mit geringeren Komplikationsraten. Die Prävention von Infektionen durch prä- bis postoperative Strategien erhöht die Sicherheit dieser Therapien.

Keywords: Cardiac implantable devices; Defibrillators; Heart failure; Pacemaker; Sudden cardiac death.

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References

Literatur

    1. Salah HM, Fudim M, Burkhoff D (2023) Device interventions for heart failure. JACC Heart Fail 11:1039–1054 - PubMed - DOI
    1. Mullens W, Dauw J, Gustafsson F et al (2024) Integration of implantable device therapy in patients with heart failure. A clinical consensus statement from the Heart Failure Association (HFA) and European Heart Rhythm Association (EHRA) of the European Society of Cardiology (ESC). Eur J Heart Fail
    1. Ellenbogen KA, Auricchio A, Burri H et al (2023) The evolving state of cardiac resynchronization therapy and conduction system pacing: 25 years of research at EP Europace journal. Europace 25:
    1. Glikson M, Nielsen JC, Kronborg MB et al (2021) 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy. Eur Heart J 42:3427–3520 - PubMed - DOI
    1. Curtis AB, Worley SJ, Chung ES et al (2016) Improvement in clinical outcomes with Biventricular versus right ventricular pacing: the BLOCK HF study. J Am Coll Cardiol 67:2148–2157 - PubMed - DOI

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