Disclosures S.S.A. received lecture fees from Bayer and Janssen. M.R.P. received grant support, advisory board fees, and consulting fees from AstraZeneca, Bayer, and Janssen; grant support from Medtronic and Philips Healthcare; and grant support and advisory board fees from Heartflow. E.S.D. received grant support from Cook and Terumo Aortic. E.M. was employed by Bayer. L.P.H. was employed by Janssen Pharmaceuticals and owned stock in Johnson & Johnson. S.D.B. was employed by Bayer during the operationalization of the VOYAGER PAD study. R.M.B. received consulting fees and lecture fees from Bayer, Bristol-Myers Squibb, and Pfizer. J.T.M., M.E.C., M.R.N., C.N.H., J.H., W.H.C., S.D.B., and M.P.B. receive salary support from Colorado Prevention Center, a nonprofit academic research organization affiliated with the University of Colorado that receives or has received research grant/consulting funding between July 2021 and July 2023 from the following organizations: Agios Pharmaceuticals, Inc, Alexion Pharma Godo Kaisha, Amgen Inc, Anthos Therapeutics, Inc, ARCA Biopharma, Inc, AstraZeneca Pharma India, AstraZeneca Pharmaceuticals LP, AstraZeneca UK Ltd, AstraZeneca Produtos Farmaceuticos, Lda, Atentiv, LLC, Bayer, Bayer (Proprietary) Limited, Bayer Aktiengesellschaft, Bayer Pharma AG, Beth Israel Deaconess Medical Center, Better Therapeutics, Bionest Partners Inc, Boston Clinical Research Institute, LLC, Bristol-Myers Squibb, CellResearch Corporation Pte Ltd, Cleerly, Inc, Colorado Department of Public Health and Environment, Cook Regentec LLC, CSL Behring LLC, Eidos Therapeutics, Inc, EPG Communication Holdings Ltd, Esperion Therapeutics, Inc, Faraday Pharmaceuticals, Inc, HeartFlow Inc, Hummingbird Bioscience PTE LTD, Insmed, Ionis Pharmaceuticals, IQVIA Inc, Janssen Pharmaceuticals, Inc, Janssen Research & Development, LLC, Janssen Scientific Affairs LLC, Lexicon Pharmaceuticals, Inc, LSG Corporation, MedImmune Limited, Medpace, Inc, Medscape, Merck Sharp & Dohme Corp, Northwell Health, Novartis Pharmaceuticals Corporation, Novo Nordisk, Osiris Therapeutics, Inc, Pfizer, PPD Development, LP, Prothena Biosciences Limited, Regeneron, Regents of the University of Colorado (also known as University of Colorado Denver), Sanifit Therapeutics SA, Sanofi, Silence Therapeutics PLC, Stanford University, Stealth BioTherapeutics Inc, The Brigham & Women’s Hospital, Inc, Thrombosis Research Institute, UCD iC42 Lab, University of Colorado Denver, University of Pittsburgh, VarmX, and WraSer, LLC. J.H. also reports owning AstraZeneca stock. M.P.B. receives support from the AHA SFRN under award numbers 18SFRN3390085 (BWH-DH SFRN Center) and 18SFRN33960262 (BWH-DH Clinical Project). M.P.B. also reports stock in Medtronic and Pfizer.