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Case Reports
. 2024 May;24(3):100216.
doi: 10.1016/j.clinme.2024.100216. Epub 2024 May 6.

Adenosine-sensitive ventricular tachycardia

Affiliations
Case Reports

Adenosine-sensitive ventricular tachycardia

Rahul K Mukherjee et al. Clin Med (Lond). 2024 May.
No abstract available

Keywords: Adenosine; Automaticity; Re-entry; Supraventricular tachycardia; Triggered activity; Ventricular tachycardia.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Effect of intravenous adenosine - 12-lead ECG demonstrating termination of broad complex tachycardia with period of AV block.
Fig. 2
Fig. 2
Intracardiac electrogram recordings during intravenous adenosine administration - a decapolar catheter (placed via right femoral vein access in the cardiac catheter laboratory) recording electrical signals is placed in the coronary sinus which records the local atrial signal from five poles (labelled ‘A’) and the far-field ventricular signal (labelled ‘V’). During the broad complex tachycardia, there is clear evidence of A–V dissociation, which proves that the diagnosis is ventricular tachycardia. Following administration of IV adenosine, there is a period of AV block and termination of tachycardia where only local atrial signals are recorded on the decapolar catheter (note P-waves on surface ECG with no QRS complexes during AV block).
Fig. 3
Fig. 3
Re-initiation of the same broad complex tachycardia seen on 12-lead ECG after wash-out of adenosine around 40 s later.

References

    1. Wilbur SL, Marchlinski FE. Adenosine as an anti-arrhythmic agent. Am J Cardiol. 1997;19:30–37. - PubMed
    1. Wilber DJ, Baerman J, Olshansky B, Kall J, Kopp D. Adenosine-sensitive ventricular tachycardia—clinical characteristics and response to catheter ablation. Circulation. 1993;87:126–134. - PubMed
    1. Lerman BB, Belardinelli L, West GA, Berne RM, DiMarco JP. Adenosine-sensitive ventricular tachycardia: evidence suggesting cyclic AMP-mediated triggered activity. Circulation. 1986;74:271–280. - PubMed
    1. Lerman BB. Ventricular tachycardia: mechanistic insights derived from adenosine. Circulation: Arrhythmia Electrophysiol. 2015;8:483–491. - PubMed
    1. Calvo N, Jongbloed M, Zeppenfeld K. Radiofrequency catheter ablation of idiopathic right ventricular outflow tract arrhythmias. Indian Pacing Electrophysiol J. 2013;13:14–33. - PMC - PubMed

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