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Multicenter Study
. 2024 Jul;51(7):905-914.
doi: 10.1111/jcpe.13984. Epub 2024 May 6.

Minimally invasive non-surgical periodontal therapy of intrabony defects: A prospective multi-centre cohort study

Jaimini Mehta  1 , Marco Montevecchi  2 , Ruben Garcia-Sanchez  1 , Olanrewaju Onabolu  3 , Antonio Liñares  4 , Fernando Eriksson  5 , Carlo Ghezzi  6 , Camilla Donghi  6 , Emily Ming-Chieh Lu  1 , Luigi Nibali  1   7
Affiliations
Multicenter Study

Minimally invasive non-surgical periodontal therapy of intrabony defects: A prospective multi-centre cohort study

Jaimini Mehta et al. J Clin Periodontol. 2024 Jul.

Abstract

Aim: To assess the potential benefits of minimally invasive non-surgical therapy (MINST) in teeth with intrabony defects and to explore factors associated with the outcomes.

Materials and methods: A multi-centre trial was conducted in 100 intrabony defects in periodontitis patients in private practice. Steps 1 and 2 periodontal therapy including MINST were provided. Clinical and radiographic data were analysed at baseline and 12 months after treatment, with the primary aim being change in radiographic defect depth at 12 months.

Results: Eighty-four patients completed the 12-month follow up. The mean total radiographic defect depth reduced by 1.42 mm and the defect angle increased by 3° (both p < .05). Statistically significant improvements in probing pocket depth (PPD) and clinical attachment level (CAL) were seen at 12 months compared to baseline (p < .001). Fifty-six defects (66.7%) achieved pocket closure (PPD ≤ 4 mm) and 49 defects (58.3%) achieved the composite outcome (PPD ≤ 4 mm and CAL gain ≥3 mm). Deeper and narrower angled defects were positively correlated with radiographic and clinical improvements, respectively.

Conclusions: Improvements in clinical and radiographic outcomes were seen after MINST. This study highlights the generalizability and wide applicability of this approach, further supporting its effectiveness in the treatment of intrabony defects.

Clinical trial registration: NCT03741374. https://clinicaltrials.gov/study/NCT03741374?cond=minimally%20invasive%20non%20surgical%20therapy&locStr=UK&country=United%20Kingdom&distance=50&rank=2.

Keywords: debridement; intrabony defects; minimally invasive non‐surgical therapy (MINST); periodontitis.

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References

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