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Case Reports
. 2024 Sep 1;43(9):885-888.
doi: 10.1097/INF.0000000000004380. Epub 2024 May 7.

Severe Impairment of T-cell Immunity and Pulmonary GvHD Are Major Risk Factors for Nontuberculous Mycobacterial Infection After Pediatric Allogeneic Hematopoietic Stem Cell Transplantation

Marina Ascunce  1 , Alejandra Coccolo  1 , Yasmina Mozo  2 , Fernando Baquero-Artigao  3   4   5   6 , Paula Rodriguez-Molino  3   4   5   6 , Carlos Toro-Rueda  7 , Paloma García-Clemente  7 , Elena Sánchez-Zapardiel  4   8 , Eduardo López-Granados  4   8   9 , Dolores Corral-Sánchez  2 , David Bueno  2   4 , Luisa Sisinni  2 , Antonio Pérez-Martínez  2   4   10 , Cristina Calvo  3   4   5   6   10 , Teresa Del Rosal  3   4   5   9
Affiliations
Case Reports

Severe Impairment of T-cell Immunity and Pulmonary GvHD Are Major Risk Factors for Nontuberculous Mycobacterial Infection After Pediatric Allogeneic Hematopoietic Stem Cell Transplantation

Marina Ascunce et al. Pediatr Infect Dis J. .

Abstract

Hematopoietic stem cell transplant recipients are prone to infectious complications. Infections caused by nontuberculous mycobacteria have increased in adults but literature in children is scarce. We report 6 episodes of disseminated or pulmonary nontuberculous mycobacteria infection among 5 pediatric hematopoietic stem cell transplant recipients. All but one were caused by Mycobacterium avium complex. Four patients died, 2 related to nontuberculous mycobacteria infection.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

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