Activity increases quantal size at the frog neuromuscular junction
- PMID: 3871401
- DOI: 10.1007/BF02005866
Activity increases quantal size at the frog neuromuscular junction
Abstract
Two h of nerve stimulation at 10 Hz or of elevated spontaneous release in hypertonic solution increased the size of miniature end-plate potentials (m.e.p.p.'s) and currents at the frog neuromuscular junction, probably by increasing the amount of acetylcholine in a quantum. Increases in quantal size may modulate synaptic transmission.