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Comment
. 2024 Jul;102(6):452-455.
doi: 10.1111/imcb.12768. Epub 2024 May 7.

Highlight of 2023: Advances in mast cells

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Comment

Highlight of 2023: Advances in mast cells

Jasmine Barra et al. Immunol Cell Biol. 2024 Jul.

Abstract

In this article for the Highlights of 2023 Series, we consider the growing understanding of mast cell heterogeneity and interactions that has developed from single cell RNA sequencing studies. We also discuss novel concepts concerning mast cell interactions with the central nervous system and evidence for their role in host defense against SARS-CoV-2 infection.

Keywords: CNS; immune defense; immune function; mast cells.

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References

REFERENCES

    1. Gentek R, Ghigo C, Hoeffel G, et al. Hemogenic endothelial fate mapping reveals dual developmental origin of mast cells. Immunity 2018; 48: 1160–1171.e5.
    1. Li Z, Liu S, Xu J, et al. Adult connective tissue‐resident mast cells originate from late erythro‐myeloid progenitors. Immunity 2018; 49: 640–653.e5.
    1. Sonoda T, Hayashi C, Kitamura Y. Presence of mast cell precursors in the yolk sac of mice. Dev Biol 1983; 97: 89–94.
    1. Dwyer DF, Ordovas‐Montanes J, Allon SJ, et al. Human airway mast cells proliferate and acquire distinct inflammation‐driven phenotypes during type 2 inflammation. Sci Immunol 2021; 6: eabb7221.
    1. Tauber M, Basso L, Martin J, et al. Landscape of mast cell populations across organs in mice and humans. J Exp Med 2023; 220: e20230570.

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