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Case Reports
. 2024 May 6;11(1):2347653.
doi: 10.1080/23320885.2024.2347653. eCollection 2024.

Carney complex: a case report of bilateral breast myxoid fibroadenomas

Demetris Savva  1   2 , Andreas Vassiliou  1 , Elena Theophanous  3 , Marios Loizou  4 , Anneza Yiallourou  4   5
Affiliations
Case Reports

Carney complex: a case report of bilateral breast myxoid fibroadenomas

Demetris Savva et al. Case Reports Plast Surg Hand Surg. .

Abstract

Carney complex is a rare autosomal dominant familiar multiple neoplasia syndrome combined with cardiocutaneous manifestations. Our report describes a Carney complex case with bilateral myxoid fibroadenomas that led to a bilateral mastectomy. An 18-year-old female patient presented at our clinic with complaints of multiple palpable lumps in her breasts bilaterally. On physical examination the patient had also multiple pigmented lentiginous lesions on her face, body and her sclerae, blue nevi on her trunk and upper extremities and a round moon-shaped face. The diagnosis of Carney syndrome was decided upon imaging, biopsies and genetic analysis. The patient underwent a bilateral mastectomy as a prophylactic treatment plan with tissue expanders' placement. Breast myxomatosis due to Carney complex is a common characteristic in female patients. Prophylactic mastectomy must be considered as a therapeutic intervention in these cases since it provides a definite treatment, with minimal side effects and excellent outcomes.

Keywords: Carney complex; breast myxomatosis; mastectomy; myxoid fibroadenomas.

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Conflict of interest statement

No potential conflict of interest was reported by the author(s).

Figures

Figure 1.
Figure 1.
Macroscopic image of myxoid fibroadenoma.
Figure 2.
Figure 2.
Histology slides with hematoxylin & eosin staining of myxoid fibroadenoma.
Figure 3.
Figure 3.
Patient before surgery.
Figure 4.
Figure 4.
Patient one-month post-mastectomy surgery and placement of tissue expanders.
Figure 5.
Figure 5.
Patient one month after silicone implant placement.
See this image and copyright information in PMC

References

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