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. 2024 May 8;14(5):e081940.
doi: 10.1136/bmjopen-2023-081940.

Relationship between self-psychological adjustment and post-traumatic growth in patients with lung cancer undergoing chemotherapy: a cross-sectional study

Na Liu #  1 , Lei Zhang #  2 , Yaxin Liu #  1 , Xuemei Ding  1 , Qing Li  3 , Gao Lixia  4 , Xiaoli Zhang  5
Affiliations

Relationship between self-psychological adjustment and post-traumatic growth in patients with lung cancer undergoing chemotherapy: a cross-sectional study

Na Liu et al. BMJ Open. .

Abstract

Objectives: This study aimed to determine the potential profiles of self-psychological adjustment in patients with lung cancer undergoing chemotherapy, including sense of coherence (SOC) and positive cognitive emotion regulation (PCER). The relationship between these profiles with post-traumatic growth (PTG) and the relevant factors of self-psychological adjustment in different profiles was analysed.

Design: Cross-sectional study.

Setting: Patients with lung cancer undergoing chemotherapy in China.

Participants: A total of 330 patients with lung cancer undergoing chemotherapy were recruited out of which 321 completed the questionnaires effectively.

Methods: Latent profile analysis was used to identify self-psychological adjustment classes based on the two subscales of the Sense of Coherence Scale and Cognitive Emotion Regulation Questionnaire. One-way analysis of variance and multinomial logistic regression were performed to examine the subgroup association with characteristics and PTG.

Results: Three latent profiles of self-psychological adjustment were identified: low level (54.5%), high SOC-low PCER (15.6%) and high PCER (29.9%). The results of univariate analysis showed a significant difference in PTG scores among different self-psychological adjustment subgroups (F=11.55, p<0.001). Patients in the high-PCER group were more likely living in urban areas (OR=2.41, 95% CI 1.17 to 4.97, p=0.02), and time since cancer diagnosis was ≥6 months and <1 year (OR=3.54, 95% CI 1.3 to 9.64, p<0.001).

Conclusion: This study revealed that most patients with lung cancer undergoing chemotherapy belonged to the low-level group. Three profiles are associated with PTG. There were differences in characteristics between patients treated with chemotherapy for lung cancer in the high-PCER and low-PCER groups. Thus, these profiles provide useful information for developing targeted individualised interventions based on demographic characteristics that would assist PTG in patients with lung cancer undergoing chemotherapy.

Keywords: aged; chronic disease; lung diseases; mental health; stress, psychological.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Line graph comparing profiles for sense of coherence-positive cognitive emotion regulation (SOC-PCER) (n=321).
See this image and copyright information in PMC

References

    1. Wéber A, Morgan E, Vignat J, et al. . Lung cancer mortality in the wake of the changing smoking epidemic: a descriptive study of the global burden in 2020 and 2040. BMJ Open 2023;13:e065303. 10.1136/bmjopen-2022-065303 - DOI - PMC - PubMed
    1. Sung H, Ferlay J, Siegel RL, et al. . Global cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2021;71:209–49. 10.3322/caac.21660 - DOI - PubMed
    1. Drareni K, Dougkas A, Giboreau A, et al. . Loss of smell in lung cancer patients undergoing chemotherapy: prevalence and relationship with food habit changes. Lung Cancer 2023;177:29–36. 10.1016/j.lungcan.2023.01.007 - DOI - PubMed
    1. Lin G, Yao Z, Kang K, et al. . Efficacy and toxicity profile of first-line treatment for extensive-stage small cell lung cancer: A Bayesian network meta-analysis. Cancer Med 2023;12:10230–42. 10.1002/cam4.5750 - DOI - PMC - PubMed
    1. Zraik IM, Heß-Busch Y. Management of chemotherapy side effects and their long-term sequelae. Urologe A 2021;60:862–71. 10.1007/s00120-021-01569-7 - DOI - PubMed

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