Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2024 Apr 7;16(4):e57789.
doi: 10.7759/cureus.57789. eCollection 2024 Apr.

Apocrine Breast Cancer: A Case Report

Affiliations
Case Reports

Apocrine Breast Cancer: A Case Report

Soumiya Samba et al. Cureus. .

Abstract

Breast cancer is the most frequent malignancy among women worldwide, including a wide range of histological subtypes, from typical expressions like invasive ductal carcinoma to less common variations like apocrine breast carcinoma. This document discusses the case of a 65-year-old female with apocrine breast cancer, who presented with a chronic mastodynia. This case highlights the importance of being aware of apocrine breast cancer.

Keywords: breast apocrine carcinoma; breast cancer; chemotherapy; malignancy; radiation therapy.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Mammogram view: a dense, fatty glandular breast lesion of type B exhibiting no skin thickening, along with opacity in the upper outer quadrant of the right breast displaying angular contours, categorized as BI-RADS 4c (red arrow)
BI-RADS: Breast Imaging-Reporting and Data System
Figure 2
Figure 2. Histological imaging revealing a carcinomatous tumor proliferation composed of apocrine-type cells, characterized by abundant eosinophilic cytoplasm and hyperchromatic nuclei within a dense fibrous stroma
Figure 3
Figure 3. Chest CT scan with contrast injection revealing a right breast nodule in the upper outer quadrant (red arrows): (A) axial section and (B) frontal section

References

    1. Myoepithelial and epithelial-myoepithelial, mesenchymal and fibroepithelial breast lesions: updates from the WHO Classification of Tumours of the Breast 2012. Tan PH, Ellis IO. J Clin Pathol. 2013;66:465–470. - PubMed
    1. Apocrine breast cancer: unique features of a predominantly triple-negative breast cancer. Saridakis A, Berger ER, Harigopal M, et al. Ann Surg Oncol. 2021;28:5610–5616. - PubMed
    1. An update on apocrine lesions of the breast. O'Malley FP, Bane A. Histopathology. 2008;52:3–10. - PubMed
    1. Breast gross cystic disease protein 15 in human breast cancer in culture. Miller WR, Shivas AA, Franchimont P, Haagensen DE. Eur J Cancer Clin Oncol. 1988;24:223–228. - PubMed
    1. Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide. Cochrane DR, Bernales S, Jacobsen BM, et al. Breast Cancer Res. 2014;16:0. - PMC - PubMed

Publication types

LinkOut - more resources