Neuroecological links of the exposome and One Health

Affiliations

¹ Latin American Brain Health Institute, Universidad Adolfo Ibañez, Santiago de Chile, Chile; Cognitive Neuroscience Center, Universidad de San Andrés, Buenos Aires, Argentina; Global Brain Health Institute (GBHI), University of California, San Francisco, San Francisco, USA; Trinity College Dublin, Dublin, Ireland. Electronic address: agustin.ibanez@gbhi.org.
² Department of Neurology, New York University Grossman School of Medicine, New York, USA; Neural Circuits, Consciousness, and Cognition Research Group, Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany.
³ International Center for Future Generations (ICFG), Brussels, Belgium; Brain Capital Alliance, San Francisco, CA, USA.
⁴ Brain Capital Alliance, San Francisco, CA, USA.
⁵ Neuro Climate Working Group, Global Consortium for Climate Health Education, Columbia University, New York, USA.
⁶ Euro-Mediterranean Economists Association, Barcelona, Spain.
⁷ UNFCCC secretariat, the UN Climate Change Global Innovation Hub, Bonn, Germany.
⁸ Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA.
⁹ Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Istanbul, Turkey; Department of Biophysics, School of Medicine, Istanbul Medipol University, Istanbul, Turkey.
¹⁰ NEATLabs, Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
¹¹ Institute of Global Health and Human Ecology (I-GHHE), School of Sciences & Engineering (SSE), The American University in Cairo (AUC), New Cairo, Egypt.
¹² Minderoo Foundation, Perth, WA, Australia; School of Biological Sciences, The University of Western Australia, Perth, WA, Australia.
¹³ Latin American Brain Health Institute, Universidad Adolfo Ibañez, Santiago de Chile, Chile.
¹⁴ Brain Capital Alliance, San Francisco, CA, USA; Euro-Mediterranean Economists Association, Barcelona, Spain; Center for Health and Biosciences, The Baker Institute for Public Policy, Rice University, Houston, TX, USA; Meadows Mental Health Policy Institute, Dallas, TX, USA; Institute for Mental and Physical Health and Clinical Translation (IMPACT), Deakin University and Barwon Health, Geelong, VIC, Australia; Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA; Department of Psychiatry and Behavioral Sciences, University of Texas Health Sciences Center, Houston, TX, USA; Houston Methodist Behavioral Health, Houston Methodist Academic Institute, Houston, TX, USA; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA.

PMID: 38723637
PMCID: PMC11189719
DOI: 10.1016/j.neuron.2024.04.016

Review

Neuroecological links of the exposome and One Health

Agustin Ibanez et al. Neuron. 2024.

. 2024 Jun 19;112(12):1905-1910.

doi: 10.1016/j.neuron.2024.04.016. Epub 2024 May 8.

Authors

Affiliations

¹ Latin American Brain Health Institute, Universidad Adolfo Ibañez, Santiago de Chile, Chile; Cognitive Neuroscience Center, Universidad de San Andrés, Buenos Aires, Argentina; Global Brain Health Institute (GBHI), University of California, San Francisco, San Francisco, USA; Trinity College Dublin, Dublin, Ireland. Electronic address: agustin.ibanez@gbhi.org.
² Department of Neurology, New York University Grossman School of Medicine, New York, USA; Neural Circuits, Consciousness, and Cognition Research Group, Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany.
³ International Center for Future Generations (ICFG), Brussels, Belgium; Brain Capital Alliance, San Francisco, CA, USA.
⁴ Brain Capital Alliance, San Francisco, CA, USA.
⁵ Neuro Climate Working Group, Global Consortium for Climate Health Education, Columbia University, New York, USA.
⁶ Euro-Mediterranean Economists Association, Barcelona, Spain.
⁷ UNFCCC secretariat, the UN Climate Change Global Innovation Hub, Bonn, Germany.
⁸ Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA.
⁹ Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Istanbul, Turkey; Department of Biophysics, School of Medicine, Istanbul Medipol University, Istanbul, Turkey.
¹⁰ NEATLabs, Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
¹¹ Institute of Global Health and Human Ecology (I-GHHE), School of Sciences & Engineering (SSE), The American University in Cairo (AUC), New Cairo, Egypt.
¹² Minderoo Foundation, Perth, WA, Australia; School of Biological Sciences, The University of Western Australia, Perth, WA, Australia.
¹³ Latin American Brain Health Institute, Universidad Adolfo Ibañez, Santiago de Chile, Chile.
¹⁴ Brain Capital Alliance, San Francisco, CA, USA; Euro-Mediterranean Economists Association, Barcelona, Spain; Center for Health and Biosciences, The Baker Institute for Public Policy, Rice University, Houston, TX, USA; Meadows Mental Health Policy Institute, Dallas, TX, USA; Institute for Mental and Physical Health and Clinical Translation (IMPACT), Deakin University and Barwon Health, Geelong, VIC, Australia; Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA; Department of Psychiatry and Behavioral Sciences, University of Texas Health Sciences Center, Houston, TX, USA; Houston Methodist Behavioral Health, Houston Methodist Academic Institute, Houston, TX, USA; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA.

PMID: 38723637
PMCID: PMC11189719
DOI: 10.1016/j.neuron.2024.04.016

Abstract

This NeuroView assesses the interplay among exposome, One Health, and brain capital in health and disease. Physical and social exposomes affect brain health, and green brain skills are required for environmental health strategies. Ibanez et al. address current gaps and strategies needed in research, policy, and technology, offering a road map for stakeholders.

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Conflict of interest statement

Declaration of interests S.D. is employed by the Minderoo Foundation, a philanthropic organization. Neither the Minderoo Foundation nor its benefactors had any influence over the conduct, the findings, or the recommendations of this work.

Figures

**Figure 1.. Brain-environmental interactions and One Health.**
The figure illustrates a framework connecting the exposome, One Health, and brain capital. The left panel displays the exposome, encompassing both physical and social dimensions. The exposome impacts the One Health approach (center panel), highlighting the links between brain, body, animal, and environmental Health. The brain capital (right panel) emphasizes the bipartite components of the internal exposome and green skills for envisioning critical actions to improve One Health. SES: socioeconomic status; SDH: social determinants of health; DNAm: DNA methylation; miRNAs: microRNAs

See this image and copyright information in PMC

References

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1. Vermeulen R, Schymanski EL, Barabási AL, and Miller GW (2020). The exposome and health: Where chemistry meets biology. Science 367, 392–396. 10.1126/science.aay3164. - DOI - PMC - PubMed
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1. Eyre HA, Ayadi R, Ellsworth W, Aragam G, Smith E, Dawson WD, Ibanez A, Altimus C, Berk M, Manji HK, et al. (2021). Building brain capital. Neuron 109, 1430–1432. 10.1016/j.neuron.2021.04.007. - DOI - PMC - PubMed
1. Ibanez A, and Eyre H (2023). Brain capital, ecological development and sustainable environments. BMJ Ment Health 26. 10.1136/bmjment-2023-300803. - DOI - PMC - PubMed

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Neuroecological links of the exposome and One Health

Affiliations

Neuroecological links of the exposome and One Health

Authors

Affiliations

Abstract

Conflict of interest statement

Figures

References

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources