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. 2024 Dec 31;20(1):2341505.
doi: 10.1080/21645515.2024.2341505. Epub 2024 May 9.

Exploring parental perspectives: Maternal RSV vaccination versus infant RSV monoclonal antibody

Bryony Treston  1 , Sarah Geoghegan  1   2
Affiliations

Exploring parental perspectives: Maternal RSV vaccination versus infant RSV monoclonal antibody

Bryony Treston et al. Hum Vaccin Immunother. .

Abstract

Respiratory Syncytial Virus poses a significant global public health threat, particularly affecting infants aged less than one year of age. Recently, two forms of passive immunization against infant RSV have been developed and brought to market; nirsevimab a long-acting monoclonal antibody (mAb) and RSV-PreF, a maternal RSV vaccine. The acceptability and uptake of these products will play a pivotal role in determining the success of any national immunization strategy aimed at safeguarding infants from RSV. It is crucial at this time to reflect on the factors that influence parental decisions surrounding immunization to facilitate more informed discussions, enhance healthcare communication, and contribute to the design of effective RSV prevention strategies that resonate with the concerns and aspirations of parents worldwide.

Keywords: RSV; RSVpreF; Respiratory syncytial virus; maternal vaccine; monoclonal antibody; nirsevimab; parental acceptability; uptake.

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Conflict of interest statement

No potential conflict of interest was reported by the author(s).

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