Enlargement of Perivascular Spaces as a Downstream Consequence of Spaceflight Analog-Induced Alterations in Cerebral Venous Hemodynamics

Peter Wostyn¹, Thomas H Mader², C Robert Gibson^{3

4}, Maiken Nedergaard^{5

6}

Affiliations

¹ Department of PsychiatryPC Sint-AmandusBeernem, Belgium.
² NASA Ophthalmology ConsultantMoab, Utah.
³ South Shore Eye CenterLeague City, Texas.
⁴ KBRHouston, Texas.
⁵ Faculty of Health and Medical SciencesCenter for Translational NeuromedicineUniversity of CopenhagenCopenhagen, Denmark.
⁶ Center for Translational NeuromedicineUniversity of Rochester Medical CenterRochester, New York.

Comment

Peter Wostyn et al. AJNR Am J Neuroradiol. 2024.

. 2024 May 9;45(5):E6.

doi: 10.3174/ajnr.A8062.

Peter Wostyn¹, Thomas H Mader², C Robert Gibson^{3

4}, Maiken Nedergaard^{5

6}

¹ Department of PsychiatryPC Sint-AmandusBeernem, Belgium.
² NASA Ophthalmology ConsultantMoab, Utah.
³ South Shore Eye CenterLeague City, Texas.
⁴ KBRHouston, Texas.
⁵ Faculty of Health and Medical SciencesCenter for Translational NeuromedicineUniversity of CopenhagenCopenhagen, Denmark.
⁶ Center for Translational NeuromedicineUniversity of Rochester Medical CenterRochester, New York.

No abstract available

Comment in

Reply.
Roberts DR, Tidwell J, Taylor JA. Roberts DR, et al. AJNR Am J Neuroradiol. 2024 May 9;45(5):E7. doi: 10.3174/ajnr.A8279. AJNR Am J Neuroradiol. 2024. PMID: 38724192 Free PMC article. No abstract available.

Longitudinal Changes in Cerebral Perfusion, Perivascular Space Volume, and Ventricular Volume in a Healthy Cohort Undergoing a Spaceflight Analog.
Tidwell JB, Taylor JA, Collins HR, Chamberlin JH, Barisano G, Sepehrband F, Turner MD, Gauthier G, Mulder ER, Gerlach DA, Roberts DR. Tidwell JB, et al. AJNR Am J Neuroradiol. 2023 Sep;44(9):1026-1031. doi: 10.3174/ajnr.A7949. Epub 2023 Aug 10. AJNR Am J Neuroradiol. 2023. PMID: 37562828 Free PMC article.

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1. Wostyn P, Mader TH, Gibson CR, et al. . Does long-duration exposure to microgravity lead to dysregulation of the brain and ocular glymphatic systems? Eye Brain 2022;14:49–58 10.2147/EB.S354710 - DOI - PMC - PubMed
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