Trans-amplifying RNA hitting new grounds: Gene regulation by microRNA
- PMID: 38725441
- PMCID: PMC11078691
- DOI: 10.1016/j.omtn.2024.102191
Trans-amplifying RNA hitting new grounds: Gene regulation by microRNA
Conflict of interest statement
The author declares no competing interests.
References
-
- Yıldız A., Hasani A., Hempel T., Köhl N., Beicht A., Becker R., Beissert T., Hubich-Rau S., Suchan M., Poleganov M.A., Sahin U. Trans-amplifying RNA expressing functional miRNA mediates target-specific gene suppression and simultaneous transgene expression. Mol. Ther. Nucleic Acids. 2024;35 doi: 10.1016/j.omtn.2024.102162. - DOI - PMC - PubMed
-
- Setten R.L., Rossi J.J., Han S.P. The current state and future directions of RNAi-based therapeutics. Nat. Rev. Drug Discov. 2019;18:421–446. - PubMed
-
- McBride J.L., Boudreau R.L., Harper S.Q., Staber P.D., Monteys A.M., Martins I., Gilmore B.L., Burstein H., Peluso R.W., Polisky B., et al. Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: Implications for the therapeutic development of RNAi. Proc. Natl. Acad. Sci. USA. 2008;105:5868–5873. - PMC - PubMed
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