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Review
. 2024;11(2):43-50.
doi: 10.1007/s40588-024-00219-8. Epub 2024 Mar 18.

Emerging Antifungal Resistance in Fungal Pathogens

Sui Ting Hui  1 , Hugh Gifford  2 , Johanna Rhodes  1   3
Affiliations
Review

Emerging Antifungal Resistance in Fungal Pathogens

Sui Ting Hui et al. Curr Clin Microbiol Rep. 2024.

Abstract

Purpose of review: Over recent decades, the number of outbreaks caused by fungi has increased for humans, plants (including important crop species) and animals. Yet this problem is compounded by emerging antifungal drug resistance in pathogenic species. Resistance develops over time when fungi are exposed to drugs either in the patient or in the environment.

Recent findings: Novel resistant variants of fungal pathogens that were previously susceptible are evolving (such as Aspergillus fumigatus) as well as newly emerging fungal species that are displaying antifungal resistance profiles (e.g. Candida auris and Trichophyton indotineae).

Summary: This review highlights the important topic of emerging antifungal resistance in fungal pathogens and how it evolved, as well as how this relates to a growing public health burden.

Keywords: Antifungal drug resistance; Aspergillus fumigatus; Candida auris; One Health; Public health; Trichophyton indotineae.

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Conflict of interest statement

Conflict of InterestJR has previously received honoraria from Gilead Sciences.

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