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. 2024 May 10;24(1):414.
doi: 10.1186/s12877-023-04632-4.

Association between ideal cardiovascular health and abnormal glucose metabolism in the elderly: evidence based on real-world data

Yongcheng Ren  1   2   3   4 , Wenwen Wang  5 , Haiyin Zou  5 , Yicun Lei  5 , Yiduo Li  5 , Zheng Li  5 , Xiaofang Zhang  5 , Lingzhen Kong  6 , Lei Yang  5 , Fuqun Cao  5 , Wei Yan  7 , Pengfei Wang  8   9
Affiliations

Association between ideal cardiovascular health and abnormal glucose metabolism in the elderly: evidence based on real-world data

Yongcheng Ren et al. BMC Geriatr. .

Abstract

Background: Limited information is available on the effect of ideal cardiovascular health (CVH) and abnormal glucose metabolism in elderly people. We aimed to analyze the prevalence of CVH behaviors, abnormal glucose metabolism, and their correlation in 65 and older people.

Methods: In this study, randomized cluster sampling, multivariate logistic regression, and mediating effects analysis were used. Recruiting was carried out between January 2020 and December 2020, and 1984 participants aged 65 years or older completed the study.

Results: The prevalence of abnormal glucose metabolism in this group was 26.7% (n = 529), among which the prevalence of impaired fasting glucose (IFG) was 9.5% (male vs. female: 8.7% vs 10.1%, P = 0.338), and the prevalence of type 2 diabetes mellitus (T2DM) was 19.0% (male vs. female: 17.8 vs. 19.8%, P = 0.256). The ideal CVH rate (number of ideal CVH metrics ≥ 5) was only 21.0%. The risk of IFG and T2DM decreased by 23% and 20% with each increase in one ideal CVH metrics, with OR (95%CI) of 0.77(0.65-0.92) and 0.80(0.71-0.90), respectively (P -trend < 0.001). TyG fully mediated the ideal CVH and the incidence of T2DM, and its mediating effect OR (95%CI) was 0.88(0.84-0.91).

Conclusions: Each increase in an ideal CVH measure may effectively reduce the risk of abnormal glucose metabolism by more than 20%.

Keywords: Abnormal glucose metabolism; Cardiovascular health; Elderly.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Study flow. CVH- cardiovascular health
Fig. 2
Fig. 2
Mediating pathway diagram of the relationship between TyG level in CVH and the incidence of T2DM. CVH- cardiovascular health, T2DM- type 2 diabetes mellitus, TyG- Triglyceride glycemic index
See this image and copyright information in PMC

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