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Review
. 2024 Apr 25;13(9):2530.
doi: 10.3390/jcm13092530.

Prostate Artery Embolization as Minimally Invasive Treatment for Benign Prostatic Hyperplasia: An Updated Systematic Review

Corrado Ini'  1 , Tiziana Vasile  2 , Pietro Valerio Foti  2   3   4 , Concetta Timpanaro  2 , Davide Giuseppe Castiglione  1 , Federica Libra  1 , Daniele Falsaperla  1 , Francesco Tiralongo  1 , Francesco Giurazza  5 , Cristina Mosconi  6 , Emanuele David  2 , Stefano Palmucci  2 , Salvatore Lavalle  7 , Massimo Venturini  8 , Antonio Basile  2
Affiliations
Review

Prostate Artery Embolization as Minimally Invasive Treatment for Benign Prostatic Hyperplasia: An Updated Systematic Review

Corrado Ini' et al. J Clin Med. .

Abstract

Background/Objectives: Benign prostatic hyperplasia (BPH) has a significant impact on the quality of life of symptomatic patients. In patients manifesting lower urinary tract symptoms (LUTS), prostatic arterial embolization (PAE) has become a topic of interest in recent years. The purpose of this systematic review is to analyze and review techniques and clinical outcomes of patients who underwent endovascular treatment of BPH, with a special focus on the comparison of surgical and endovascular procedures. Methods: Through the major scientific databases, 1225 articles were selected from the initial research utilizing specific keywords and medical subject headings. Based on the inclusion and exclusion criteria established for selecting relevant studies for our purposes, the systematic analysis of the literature was conducted on a total of seven articles. Results: We collected data on 718 male patients (408 patients underwent PAE and 310 received TURP). The technical success rate varied from 86% to 100% for TAE and was 100% for TURP. During a 12-month follow-up period, both PAE and TURP were comparable on the reduction in IPSS and QoL questionnaire, while TURP showed significant improvements in Qmax and in the reduction in prostate volume. Length and cost of hospitalization were lower for PAE. Complication and adverse events rates were higher in the TURP group rather than in the PAE group (60.6% vs. 35.5%). Conclusions: Prostatic artery embolization represents an emerging minimally invasive procedure for BPH. According to previously released clinical studies, quality-of-life and urological symptom scores of the PAE group were comparable to those of the TURP group. Our research strengthens the evidence supporting the effectiveness and safety of PAE as a therapy for LUTS related to BPH.

Keywords: benign prostatic hyperplasia (C12.100.500.565.500, C12.200.294.565.500); embolization; therapeutic (E02.520.360, E02.926.500); transurethral resection of prostate (E04.950.774.860.625.750).

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Flow-chart showing selection process of the articles included in the study.
Figure 2
Figure 2
Risk of bias [16,17,18,19,20,21,22].
See this image and copyright information in PMC

References

    1. Devlin C.M., Simms M.S., Maitland N.J. Benign prostatic hyperplasia—What do we know? BJU Int. 2021;127:389–399. doi: 10.1111/bju.15229. - DOI - PubMed
    1. Vuichoud C., Loughlin K.R. Benign prostatic hyperplasia: Epidemiology, economics and evaluation. Can. J. Urol. 2015;22:1–6. - PubMed
    1. Egan K.B. The Epidemiology of Benign Prostatic Hyperplasia Associated with Lower Urinary Tract Symptoms: Prevalence and Incident Rates. Urol. Clin. N. Am. 2016;43:289–297. doi: 10.1016/j.ucl.2016.04.001. - DOI - PubMed
    1. Oelke M., Bachmann A., Descazeaud A., Emberton M., Gravas S., Michel M.C., N’dow J., Nordling J., de la Rosette J.J. European Association of Urology. EAU guidelines on the treatment and follow-up of non-neurogenic male lower urinary tract symptoms including benign prostatic obstruction. Eur. Urol. 2013;64:118–140. doi: 10.1016/j.eururo.2013.03.004. - DOI - PubMed
    1. Csikós E., Horváth A., Ács K., Papp N., Balázs V.L., Dolenc M.S., Kenda M., Kočevar Glavač N., Nagy M., Protti M., et al. Treatment of Benign Prostatic Hyperplasia by Natural Drugs. Molecules. 2021;26:7141. doi: 10.3390/molecules26237141. - DOI - PMC - PubMed

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