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Review
. 2024 Apr 30;29(9):2073.
doi: 10.3390/molecules29092073.

Therapeutic Applications of Nanomedicine: Recent Developments and Future Perspectives

Farah Rehan  1 , Mingjie Zhang  2   3 , Jun Fang  2 , Khaled Greish  1
Affiliations
Review

Therapeutic Applications of Nanomedicine: Recent Developments and Future Perspectives

Farah Rehan et al. Molecules. .

Abstract

The concept of nanomedicine has evolved significantly in recent decades, leveraging the unique phenomenon known as the enhanced permeability and retention (EPR) effect. This has facilitated major advancements in targeted drug delivery, imaging, and individualized therapy through the integration of nanotechnology principles into medicine. Numerous nanomedicines have been developed and applied for disease treatment, with a particular focus on cancer therapy. Recently, nanomedicine has been utilized in various advanced fields, including diagnosis, vaccines, immunotherapy, gene delivery, and tissue engineering. Multifunctional nanomedicines facilitate concurrent medication delivery, therapeutic monitoring, and imaging, allowing for immediate responses and personalized treatment plans. This review concerns the major advancement of nanomaterials and their potential applications in the biological and medical fields. Along with this, we also mention the various clinical translations of nanomedicine and the major challenges that nanomedicine is currently facing to overcome the clinical translation barrier.

Keywords: gene therapy; immunotherapy; nanomedicine applications; theranostic; tissue engineering; vaccine development.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Novel applications of nanomedicine in various biomedical and therapeutic fields.
Figure 2
Figure 2
The value of nanomedicine in vaccine development with special emphasis on COVID vaccine development.
See this image and copyright information in PMC

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