Autonomic neuropathy improving after intravenous immunoglobulin therapy

Claudia Alberti^#¹, Jacopo Spagliardi^#¹, Franca Barbic^{2

3}, Pietro Emiliano Doneddu^{4

5}, Claudia Cutellè¹, Raffaello Furlan^{2

3}, Eduardo Nobile-Orazio^{1

6}

Affiliations

¹ Neuromuscular and Neuroimmunology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089, Milan, Italy.
² Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072, Milan, Italy.
³ Department of Internal Medicine, IRCCS Humanitas Research Hospital, Milan, Italy.
⁴ Neuromuscular and Neuroimmunology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089, Milan, Italy. pietro.e.doneddu@gmail.com.
⁵ Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072, Milan, Italy. pietro.e.doneddu@gmail.com.
⁶ Department of Medical Biotechnology and Translational Medicine, Milan University, Milan, Italy.

^# Contributed equally.

Case Reports

Claudia Alberti et al. Clin Auton Res. 2024 Apr.

. 2024 Apr;34(2):311-316.

doi: 10.1007/s10286-024-01034-3. Epub 2024 May 11.

Claudia Alberti^#¹, Jacopo Spagliardi^#¹, Franca Barbic^{2

3}, Pietro Emiliano Doneddu^{4

5}, Claudia Cutellè¹, Raffaello Furlan^{2

3}, Eduardo Nobile-Orazio^{1

6}

¹ Neuromuscular and Neuroimmunology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089, Milan, Italy.
² Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072, Milan, Italy.
³ Department of Internal Medicine, IRCCS Humanitas Research Hospital, Milan, Italy.
⁴ Neuromuscular and Neuroimmunology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089, Milan, Italy. pietro.e.doneddu@gmail.com.
⁵ Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072, Milan, Italy. pietro.e.doneddu@gmail.com.
⁶ Department of Medical Biotechnology and Translational Medicine, Milan University, Milan, Italy.

^# Contributed equally.

No abstract available

References

1. Koike H, Watanabe H, Sobue G (2013) The spectrum of immune-mediated autonomic neuropathies: insights from the clinicopathological features. J Neurol Neurosurg Psychiatry 84:98–106. https://doi.org/10.1136/jnnp-2012-302833 - DOI - PubMed
1. Golden EP, Bryarly MA, Vernino S (2018) Seronegative autoimmune autonomic neuropathy: a distinct clinical entity. Clin Auton Res 28:115–123. https://doi.org/10.1007/s10286-017-0493-8 - DOI - PubMed
1. Tijero B, Del Pino R, Pérez-Concha T et al. (2018) Seronegative and seropositive autoimmune autonomic ganglionopathy (AAG): same clinical picture, same response to immunotherapy. J Neuroimmunol 319:68–70. https://doi.org/10.1016/j.jneuroim.2018.03.018 - DOI - PubMed
1. Iodice V, Kimpinski K, Vernino S, Sandroni P, Fealey RD, Low PA (2009) Efficacy of immunotherapy in seropositive and seronegative putative autoimmune autonomic ganglionopathy. Neurology 72:2002–2008. https://doi.org/10.1212/WNL.0b013e3181a92b52 - DOI - PubMed - PMC
1. Barbic F, Dipaola F, Andreetta F et al. (2017) Long-term cardiovascular autonomic and clinical changes after immunoglobulin G immunoadsorption therapy in autoimmune autonomic ganglionopathy. J Hypertens 35:1513–1520. https://doi.org/10.1097/HJH.0000000000001355 - DOI - PubMed