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. 1985 Jun 3;185(1):147-50.
doi: 10.1016/0014-5793(85)80759-6.

GTP enhances inositol trisphosphate-stimulated Ca2+ release from rat liver microsomes

A P Dawson
Free article

GTP enhances inositol trisphosphate-stimulated Ca2+ release from rat liver microsomes

A P Dawson. FEBS Lett. .
Free article

Abstract

Low concentrations of GTP (10-50 microM) greatly enhance the inositol 1,4,5-trisphosphate stimulated Ca2+ release from rat liver microsomal vesicles. The effect of GTP depends on the presence of low concentrations of polyethylene glycol in the incubation medium. Guanylyl imidodiphosphate is ineffective at mimicking the GTP effect and inhibits the action of GTP added subsequently.

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