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Meta-Analysis
. 2024 Oct;46(5):1024-1033.
doi: 10.1007/s11096-024-01742-w. Epub 2024 May 11.

Medication errors in emergency departments: a systematic review and meta-analysis of prevalence and severity

Phuong Thi Lan Nguyen  1 , Thu Anh Thi Phan #  1 , Van Bich Ngoc Vo  1 , Nhi T N Ngo  2 , Ha Thi Nguyen  1 , Toi Lam Phung  3 , Mai Thi Tuyet Kieu  4 , Thao Huong Nguyen  5 , Khanh N C Duong  6   7
Affiliations
Meta-Analysis

Medication errors in emergency departments: a systematic review and meta-analysis of prevalence and severity

Phuong Thi Lan Nguyen et al. Int J Clin Pharm. 2024 Oct.

Abstract

Background: Medication errors significantly compromise patient safety in emergency departments. Although previous studies have investigated the prevalence of these errors in this setting, results have varied widely.

Aim: The aim was to report pooled data on the prevalence and severity of medication errors in emergency departments, as well as the proportion of patients affected by these errors.

Method: Systematic searches were conducted in Embase, PubMed, and the Cochrane Library from database inception until June 2023. Studies provided numerical data on medication errors within emergency departments were eligible for inclusion. Random-effects meta-analysis was employed to pool the prevalence of medication errors, the proportion of patients experiencing these errors, and the error severity levels. Heterogeneity among studies was assessed using the I2 statistic and Cochran's Q test.

Results: Twenty-four studies met the inclusion criteria. The meta-analysis gave a pooled prevalence of medication errors in emergency departments of 22.6% (95% Confidence Interval [CI] 19.2-25.9%, I2 = 99.9%, p < 0.001). The estimated proportion of patients experiencing medication errors was 36.3% (95% CI 28.3-44.3%, I2 = 99.8%, p < 0.001). Of these errors, 42.6% (95% CI 5.0-80.1%) were potentially harmful but not life-threatening, while no-harm errors accounted for 57.3% (95% CI 14.1-100.0%).

Conclusion: The prevalence of medication errors, particularly those potentially harmful, underscores potential safety issues in emergency departments. It is imperative to develop and implement effective interventions aimed at reducing medication errors and enhancing patient safety in this setting.

Keywords: Emergency service; Hospital; Medication errors; Meta-analysis; Prevalence; Systematic review.

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References

    1. Dietz I, Borasio GD, Schneider G, et al. Medical errors and patient safety in palliative care: a review of current literature. J Palliat Med. 2010;13(12):1469–74. https://doi.org/10.1089/jpm.2010.0228 . - DOI - PubMed
    1. Ehsani SR, Cheraghi MA, Nejati A, et al. Medication errors of nurses in the emergency department. J Med Ethics Hist Med. 2013;6:11. - PubMed - PMC
    1. Acheampong F, Anto BP, Koffuor GA. Medication safety strategies in hospitals–a systematic review. Int J Risk Saf Med. 2014;26(3):117–31. https://doi.org/10.3233/jrs-140623 . - DOI - PubMed
    1. Nikpeyma N, Gholamnejad H. Reason for medication errors in nurses’ views. Adv Nurs Midwifery. 2009;19:18–24.
    1. National Coordinating Council for Medication Error Reporting and Prevention. About Medication Errors. In: The National Coordinating Council for Medication Error Reporting and Prevention (NCC MERP). https://www.nccmerp.org/about-medication-errors . Accessed 30 June 2023.

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