Comments on "Clinically relevant therapeutic approaches against acetaminophen (APAP) hepatotoxicity and acute liver failure"
- PMID: 38735443
- DOI: 10.1016/j.bcp.2024.116276
Comments on "Clinically relevant therapeutic approaches against acetaminophen (APAP) hepatotoxicity and acute liver failure"
Keywords: Acetaminophen; Aladote; Calmangafodipir; Clinical trials; Hepatotoxicity; Liver failure.
Conflict of interest statement
Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: J.O.G.K. and P.J. are founders of PledPharma AB.; J.O.G.K. is a former employee of PledPharma; P.J. is a former scientific advisors to PledPharma; J.O.G.K. is the first inventor on three granted patent families (e.g., US8377969, US8633174, US9187509 and US10688087) covering the therapeutic use of calmangafodipir [Ca(4)Mn(DPDP)(5)], which are owned by PledPharma/Egetis; J.O.G.K. and P.J. are, furthermore, inventors on a granted patent family (e.g., US10888553) covering the therapeutic use of fodipir (DPDP) to treat platinum-induced peripheral sensory neuropathy, which is owned by Karlsson-Tuner Invest AS; P.J. is scientific advisor to and owns shares in IC Targets AS, a company developing mangafodipir (MnDPDP) as a contrast agent for MRI..
Comment on
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Clinically relevant therapeutic approaches against acetaminophen hepatotoxicity and acute liver failure.Biochem Pharmacol. 2024 Oct;228:116056. doi: 10.1016/j.bcp.2024.116056. Epub 2024 Feb 10. Biochem Pharmacol. 2024. PMID: 38346541 Free PMC article. Review.
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