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Case Reports
. 2024 Jul 1;49(7):e338-e339.
doi: 10.1097/RLU.0000000000005264. Epub 2024 May 9.

Increased PSMA-Targeted 18 F-DCFPyL Uptake in Peripheral T-Cell Lymphoma

Charles J Milrod  1 , Cory Brown  2 , Anthony E Mega  1
Affiliations
Case Reports

Increased PSMA-Targeted 18 F-DCFPyL Uptake in Peripheral T-Cell Lymphoma

Charles J Milrod et al. Clin Nucl Med. .

Abstract

Peripheral T-cell lymphomas are a heterogenous group of lymphomas with a high rate of extranodal disease. We present a case of increased 18 F-DCFPyL uptake in peripheral T-cell lymphoma of subcutaneous tissue and bone. Familiarity with the increased 18 F-DCFPyL uptake and extranodal presentation of peripheral T-cell lymphomas can avoid misinterpretation for metastatic disease.

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Conflict of interest statement

Conflicts of interest and sources of funding: A.M. reports consultancy for Bristol Myers Squibb. The rest of the authors have no conflicts of interest declared.

References

    1. Weisenburger DD, Savage KJ, Harris NL, et al. Peripheral T-cell lymphoma, not otherwise specified: a report of 340 cases from the international peripheral T-cell lymphoma project. Blood . 2011;117:3402–3408.
    1. Hofman MS, Lawrentschuk N, Francis RJ, et al. Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective, randomised, multicentre study. Lancet . 2020;395:1208–1216.
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    1. Caputo SA, Jang A, Talbert J, et al. Prostate-specific membrane antigen PET positivity in a lung mass: diagnosis of diffuse large B-cell lymphoma. Clin Nucl Med . 2023;48:190–191.
    1. Dendl K, Merkel A, Kratochwil C, et al. Positive multifocal PSMA PET/CT in a patient with prostate cancer and follicular lymphoma. Clin Nucl Med . 2022;47:e47–e48.

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