Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Jun;15(2):409-413.
doi: 10.1007/s13193-024-01921-1. Epub 2024 Mar 11.

Askin's Tumor in the Chest Wall-a Rare Clinical Entity and Review of Literature

Manish Sahni  1 , Shefali Goyal  2 , Sanjeev Devgarha  2 , Anula Sisodiya  2
Affiliations
Review

Askin's Tumor in the Chest Wall-a Rare Clinical Entity and Review of Literature

Manish Sahni et al. Indian J Surg Oncol. 2024 Jun.

Abstract

Askin tumors are the rare malignancy of neuroectodermal origin of the thoracic wall. Its prevalence is more in younger age group who present with vague symptoms leading to delayed diagnosis. We hereby present a case report of complex management of large chest wall tumor in a young boy and review the literature of this entity.

Keywords: IHC (immunohistochemistry); NACT (neoadjuvant chemotherapy); OS (overall survival); POD (postoperative day); SE/PPNETS (Ewing’s sarcoma/peripheral primitive neuroectodermal tumor); SUV (standard uptake value).

PubMed Disclaimer

Conflict of interest statement

Conflict of InterestThe authors declare no competing interests.

Figures

Fig. 1
Fig. 1
A Clinical picture of right chest wall tumor. B Chest X ray showing right sided homogenous opacity. C CT scan chest depicting chest wall tumor with intrathoracic extension
Fig. 2
Fig. 2
A Intraoperative picture of chest wall tumor. 2 B Intrathoracic extension of tumor to upper and middle lobe of right lung. C Chest wall reconstruction with prolene mesh. D Mesh cover with Pectoralis major muscle and soft tissue with skin closure. E Postoperative healed wound
Fig. 3
Fig. 3
A Gross specimen of chest wall tumor. B Microscopic appearance -small round cell tumor cells. C IHC marker with CD 99 positive tumor cells
See this image and copyright information in PMC

References

    1. Laskar S, Nair C, Mallik S, et al. Prognostic factors and outcome in Askin–-Rosai tumor: a review of 104 patients. Int J Radiat Oncol. 2011;79:202–207. doi: 10.1016/j.ijrobp.2009.10.039. - DOI - PubMed
    1. Askin FB, Rosai J, Sibley RK, Dehner LP, McAlister WH. Malignant small cell tumor of the thoracopulmonary region in childhood: a distinctive clinicopathologic entity of uncertain histogenesis. Cancer. 1979;43:2438–2451. doi: 10.1002/1097-0142(197906)43:6<2438::AID-CNCR2820430640>3.0.CO;2-9. - DOI - PubMed
    1. Ushigome S, Machinami R, Sorensen PH (2002) Sarcoma/primitive neuroectodermal tumour. In: World Health Organization Classification of Tumors. Pathology and Genetics of Tumours of Soft Tissue and Bone. 1st ed; 298–300
    1. Sabaté JM, Franquet T, Parellada JA, Monill JM, Oliva E. Malignant neuroectodermal tumour of the chest wall (Askin tumour): CT and MR findings in eight patients. Clin Radiol. 1994;49:634–638. doi: 10.1016/S0009-9260(05)81882-3. - DOI - PubMed
    1. Demir A, Gunluoglu MZ, Dagoglu N, et al. Surgical treatment and prognosis of primitive neuroectodermal tumors of the thorax. J Thorac Oncol. 2009;4:185–192. doi: 10.1097/JTO.0b013e318194fafe. - DOI - PubMed

LinkOut - more resources