doi: 10.1002/eji.1830090816.
Wheat germ agglutinin activates macrophages for collaboration with B cells
- PMID: 387424
- DOI: 10.1002/eji.1830090816
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Wheat germ agglutinin activates macrophages for collaboration with B cells
Eur J Immunol.
1979 Aug.
Abstract
Wheat germ agglutinin (WGA), added to Mishell-Dutton-type cultures of nude spleen cells challenged with erythrocyte antigens, allows a primary specific plaque-forming cell (PFC) response. WGA, however, does not display direct mitogenicity to either T or B lymphocytes. The activity of WGA in the specific PFC response is macrophage-dependent and parallels a nonspecific PFC response in the same cultures.
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