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Comment
. 2024 Jun;20(6):315.
doi: 10.1038/s41582-024-00972-w.

CAR T cells offer hope in glioblastoma

Ian Fyfe  1
Affiliations
Comment

CAR T cells offer hope in glioblastoma

Ian Fyfe. Nat Rev Neurol. 2024 Jun.
No abstract available

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Comment on

  • Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results.
    Bagley SJ, Logun M, Fraietta JA, Wang X, Desai AS, Bagley LJ, Nabavizadeh A, Jarocha D, Martins R, Maloney E, Lledo L, Stein C, Marshall A, Leskowitz R, Jadlowsky JK, Christensen S, Oner BS, Plesa G, Brennan A, Gonzalez V, Chen F, Sun Y, Gladney W, Barrett D, Nasrallah MP, Hwang WT, Ming GL, Song H, Siegel DL, June CH, Hexner EO, Binder ZA, O'Rourke DM. Bagley SJ, et al. Nat Med. 2024 May;30(5):1320-1329. doi: 10.1038/s41591-024-02893-z. Epub 2024 Mar 13. Nat Med. 2024. PMID: 38480922 Clinical Trial.

References

Original articles
    1. Choi, B. D. et al. Intraventricular CARv3-TEAM-E T cells in recurrent glioblastoma. N. Engl. J. Med. 390, 1290–1298 (2024) - DOI - PubMed
    1. Bagley, S. J. et al. Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results. Nat. Med. https://doi.org/10.1038/s41591-024-02893-z (2024) - DOI - PubMed

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