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Review
. 2024 Jul;26(7):735-743.
doi: 10.1007/s11912-024-01539-0. Epub 2024 May 15.

Axillary Management: How Much Is Too Much?

Nicci Owusu-Brackett  1 , Benjin Facer  2 , Dionisia Quiroga  3 , Ashley Pariser  3 , Michael Grimm  4 , Sasha Beyer  2 , Sachin Jhawar  2 , Bridget A Oppong  5
Affiliations
Review

Axillary Management: How Much Is Too Much?

Nicci Owusu-Brackett et al. Curr Oncol Rep. 2024 Jul.

Abstract

Purpose of review: To review the current management of the axilla in breast cancer.

Recent findings: Axillary dissection is no longer indicated in patients with clinically node-negative axilla with 1-2 positive sentinel lymph nodes following upfront surgery or in patients with clinically node-negative axilla following neoadjuvant chemotherapy. Breast cancer has evolved away from routine axillary clearance to the less invasive sentinel lymph node biopsy to now complete omission of axillary sampling in select patients. We will review the most salient evidence that has shaped these practice changes over the last three decades. Current practice controversies are especially relevant for elderly populations and those receiving neoadjuvant therapy. Ongoing clinical trials will provide data to further guide breast cancer surgical management.

Keywords: Axilla; Breast Cancer; Neoadjuvant Systemic Therapy; Nodal Irradiation; Surgery.

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Conflict of interest statement

The authors declare no competing interests.

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Summary of Axillary Management Algorithm
See this image and copyright information in PMC

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