Abemaciclib-based therapy versus tucidinostat-based therapy in patients with HR+HER2- metastatic breast cancer after palbociclib progression: insights and challenges from a comparative cohort study in China
- PMID: 38751484
- PMCID: PMC11093083
- DOI: 10.21037/tbcr-23-45
Abemaciclib-based therapy versus tucidinostat-based therapy in patients with HR+HER2- metastatic breast cancer after palbociclib progression: insights and challenges from a comparative cohort study in China
Keywords: Hormone receptor-positive human epidermal growth factor receptor-2-negative metastatic breast cancer (HR+HER2− MBC); abemaciclib; personalized medicine; tucidinostat.
Conflict of interest statement
Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://tbcr.amegroups.org/article/view/10.21037/tbcr-23-45/coif). NB has served on the advisory board for Gilead. NJR is a full-time employee for Ontada. The authors have no other conflicts of interest to declare.
Comment on
- Transl Breast Cancer Res. 4:10.
Similar articles
-
Efficacy and safety of abemaciclib-based therapy versus tucidinostat-based therapy after progression on palbociclib in patients with HR+HER2- metastatic breast cancer.Transl Breast Cancer Res. 2023 Apr 30;4:10. doi: 10.21037/tbcr-23-9. eCollection 2023. Transl Breast Cancer Res. 2023. PMID: 38751483 Free PMC article.
-
Abemaciclib plus endocrine therapy versus chemotherapy after progression on prior palbociclib in HR+/HER2- metastatic breast cancer: A single center real-world study in China.Cancer Med. 2024 May;13(10):e7249. doi: 10.1002/cam4.7249. Cancer Med. 2024. PMID: 38770648 Free PMC article.
-
Navigating next-generation HR+/HER2- metastatic breast cancer therapies: a critical commentary on abemaciclib vs. tucidinostat after palbociclib progression.Transl Breast Cancer Res. 2023 Oct 23;4:31. doi: 10.21037/tbcr-23-41. eCollection 2023. Transl Breast Cancer Res. 2023. PMID: 38751459 Free PMC article. No abstract available.
-
A narrative review of the clinical development of CDK4/6 inhibitor abemaciclib in breast cancer.Transl Breast Cancer Res. 2022 Jan 31;3:4. doi: 10.21037/tbcr-21-36. eCollection 2022. Transl Breast Cancer Res. 2022. PMID: 38751545 Free PMC article. Review.
-
Practical Guidance on Abemaciclib in Combination with Adjuvant Endocrine Therapy for Treating Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative High-Risk Early Breast Cancer.Breast Cancer (Dove Med Press). 2024 Aug 29;16:517-527. doi: 10.2147/BCTT.S271441. eCollection 2024. Breast Cancer (Dove Med Press). 2024. PMID: 39224861 Free PMC article. Review.
Cited by
-
Efficacy and safety of tucidinostat in patients with advanced hormone receptor-positive human epidermal growth factor receptor 2-negative breast cancer: real-world insights.Ann Transl Med. 2023 Dec 20;11(12):409. doi: 10.21037/atm-23-1913. Epub 2023 Dec 19. Ann Transl Med. 2023. PMID: 38213803 Free PMC article.
References
-
- NCCN Clinical Practice Guidelines in Oncology—Breast Cancer Version 4.2023. Accessed August 31, 2023. Available online: https://www.nccn.org/professionals/physician_gls/pdf/breast.pdf
Publication types
LinkOut - more resources
Full Text Sources
Research Materials
Miscellaneous