New partners for Luspatercept in β-thalassemia
- PMID: 38752378
- DOI: 10.1002/ajh.27362
New partners for Luspatercept in β-thalassemia
Comment on
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Bone marrow Tfr2 deletion improves the therapeutic efficacy of the activin-receptor ligand trap RAP-536 in β-thalassemic mice.Am J Hematol. 2024 Jul;99(7):1313-1325. doi: 10.1002/ajh.27336. Epub 2024 Apr 17. Am J Hematol. 2024. PMID: 38629683
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Combination of a TGF-β ligand trap (RAP-GRL) and TMPRSS6-ASO is superior for correcting β-thalassemia.Am J Hematol. 2024 Jul;99(7):1300-1312. doi: 10.1002/ajh.27332. Epub 2024 Apr 25. Am J Hematol. 2024. PMID: 38659383 Free PMC article.
References
REFERENCES
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- Vinchi F, Platzbecker U. Luspatercept: a peaceful revolution in the standard of care for myelodysplastic neoplasms. Hema. 2024;8(3):e41.
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- Guerra A, Hamilton N, Rivera A, Demsko P, Guo S, Rivella S. Combination of a TGF‐β ligand trap (RAP‐GRL) and TMPRSS6‐ASO is superior for correcting β‐thalassemia. Am J Hematol. 2024;99(7):1300‐1312. doi:10.1002/ajh.27332
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- Tanzi E, Di Modica SM, Bordini J, et al. Bone marrow Tfr2 deletion improves the therapeutic efficacy of the activin‐receptor ligand trap RAP‐536 in β‐thalassemic mice. Am J Hematol. 2024;99(7):1313‐1325. doi:10.1002/ajh.27336
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- Casu C, Aghajan M, Oikonomidou PR, Guo S, Monia BP, Rivella S. Combination of Tmprss6‐ ASO and the iron chelator deferiprone improves erythropoiesis and reduces iron overload in a mouse model of beta‐thalassemia intermedia. Haematologica. 2016;101(1):e8‐e11.
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- Casu C, Pettinato M, Liu A, et al. Correcting β‐thalassemia by combined therapies that restrict iron and modulate erythropoietin activity. Blood. 2020;136(17):1968‐1979.
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