Integration of GPT-4 into multimodal bioinformatics for surgical specimens

doi:10.1097/JS9.0000000000001617

. 2024 Sep 1;110(9):5854-5856.

doi: 10.1097/JS9.0000000000001617.

Integration of GPT-4 into multimodal bioinformatics for surgical specimens

Siqi Fan^{1

2}, Yue Zheng^{1

3}, Xu Sun⁴, Ailin Zhao^{1

4}, Yijun Wu^{1

3}

Affiliations

¹ Division of Thoracic Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University.
² West China School of Medicine, Sichuan University, Chengdu, Sichuan, People's Republic of China.
³ Laboratory of Clinical Cell Therapy, West China Hospital, Sichuan University.
⁴ Department of Hematology, West China Hospital, Sichuan University.

PMID: 38752480
PMCID: PMC11392188
DOI: 10.1097/JS9.0000000000001617

Integration of GPT-4 into multimodal bioinformatics for surgical specimens

Siqi Fan et al. Int J Surg. 2024.

. 2024 Sep 1;110(9):5854-5856.

doi: 10.1097/JS9.0000000000001617.

Authors

Siqi Fan^{1

2}, Yue Zheng^{1

3}, Xu Sun⁴, Ailin Zhao^{1

4}, Yijun Wu^{1

3}

Affiliations

¹ Division of Thoracic Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University.
² West China School of Medicine, Sichuan University, Chengdu, Sichuan, People's Republic of China.
³ Laboratory of Clinical Cell Therapy, West China Hospital, Sichuan University.
⁴ Department of Hematology, West China Hospital, Sichuan University.

PMID: 38752480
PMCID: PMC11392188
DOI: 10.1097/JS9.0000000000001617

No abstract available

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Conflict of interest statement

There are no conflicts of interest.

Figures

**Figure 1**
The role of GPT in multimodality bioinformatics research. (A) ChatGPT in bioinformatics research. (B) Example of applying ChatGPT to design a bioinformatics research program. (C) Tests of ChatGPT in aiding data analysis.

See this image and copyright information in PMC

References

1. Zhu L, Mou W, Lai Y, et al. . Step into the era of large multimodal models: a pilot study on ChatGPT-4V(ision)’s ability to interpret radiological images. Int J Surg 2024. [Epub ahead of print]. - PMC - PubMed
1. Hou W, Ji Z. Assessing GPT-4 for cell type annotation in single-cell RNA-seq analysis. Nat Methods 2024. [Epub ahead of print]. - PMC - PubMed
1. Jin Q, Yang Y, Chen Q, et al. . GeneGPT: augmenting large language models with domain tools for improved access to biomedical information. Bioinformatics 2024;40:btae075. - PMC - PubMed
1. Li Y, Li Z, Zhang K, et al. . ChatDoctor: a medical chat model fine-tuned on a large language model meta-AI (LLaMA) using medical domain knowledge. Cureus 2023;15:e40895. - PMC - PubMed
1. Wu C, Lin W, Zhang X, et al. . PMC-LLaMA: toward building open-source language models for medicine. J Am Med Inform Assoc 2024;13:ocae045. - PMC - PubMed

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[1] Zhu L, Mou W, Lai Y, et al. . Step into the era of large multimodal models: a pilot study on ChatGPT-4V(ision)’s ability to interpret radiological images. Int J Surg 2024. [Epub ahead of print]. - PMC - PubMed

[2] Zhu L, Mou W, Lai Y, et al. . Step into the era of large multimodal models: a pilot study on ChatGPT-4V(ision)’s ability to interpret radiological images. Int J Surg 2024. [Epub ahead of print]. - PMC - PubMed

[3] Hou W, Ji Z. Assessing GPT-4 for cell type annotation in single-cell RNA-seq analysis. Nat Methods 2024. [Epub ahead of print]. - PMC - PubMed

[4] Hou W, Ji Z. Assessing GPT-4 for cell type annotation in single-cell RNA-seq analysis. Nat Methods 2024. [Epub ahead of print]. - PMC - PubMed

[5] Jin Q, Yang Y, Chen Q, et al. . GeneGPT: augmenting large language models with domain tools for improved access to biomedical information. Bioinformatics 2024;40:btae075. - PMC - PubMed

[6] Jin Q, Yang Y, Chen Q, et al. . GeneGPT: augmenting large language models with domain tools for improved access to biomedical information. Bioinformatics 2024;40:btae075. - PMC - PubMed

[7] Li Y, Li Z, Zhang K, et al. . ChatDoctor: a medical chat model fine-tuned on a large language model meta-AI (LLaMA) using medical domain knowledge. Cureus 2023;15:e40895. - PMC - PubMed

[8] Li Y, Li Z, Zhang K, et al. . ChatDoctor: a medical chat model fine-tuned on a large language model meta-AI (LLaMA) using medical domain knowledge. Cureus 2023;15:e40895. - PMC - PubMed

[9] Wu C, Lin W, Zhang X, et al. . PMC-LLaMA: toward building open-source language models for medicine. J Am Med Inform Assoc 2024;13:ocae045. - PMC - PubMed

[10] Wu C, Lin W, Zhang X, et al. . PMC-LLaMA: toward building open-source language models for medicine. J Am Med Inform Assoc 2024;13:ocae045. - PMC - PubMed

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Integration of GPT-4 into multimodal bioinformatics for surgical specimens

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Integration of GPT-4 into multimodal bioinformatics for surgical specimens

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