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. 1985 Jun;27(6):980-1.
doi: 10.1128/AAC.27.6.980.

Studies with temocillin in a hamster model of antibiotic-associated colitis

Studies with temocillin in a hamster model of antibiotic-associated colitis

R J Boon et al. Antimicrob Agents Chemother. 1985 Jun.

Abstract

Hamsters given the new penicillin temocillin, either orally or by injection, did not develop antibiotic-associated colitis, whereas animals given the control antibiotics cefoxitin or clindamycin developed the disease, which is characterized by marked hemorrhagic cecitis and high cecal levels of Clostridium difficile cytotoxin.

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References

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