Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 May 16;3(5):e0000519.
doi: 10.1371/journal.pdig.0000519. eCollection 2024 May.

Mapping the ethical landscape of digital biomarkers: A scoping review

Mattia Andreoletti  1 , Luana Haller  1 , Effy Vayena  1 , Alessandro Blasimme  1
Affiliations

Mapping the ethical landscape of digital biomarkers: A scoping review

Mattia Andreoletti et al. PLOS Digit Health. .

Abstract

In the evolving landscape of digital medicine, digital biomarkers have emerged as a transformative source of health data, positioning them as an indispensable element for the future of the discipline. This necessitates a comprehensive exploration of the ethical complexities and challenges intrinsic to this cutting-edge technology. To address this imperative, we conducted a scoping review, seeking to distill the scientific literature exploring the ethical dimensions of the use of digital biomarkers. By closely scrutinizing the literature, this review aims to bring to light the underlying ethical issues associated with the development and integration of digital biomarkers into medical practice.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Scoping Literature Review flow chart (PRISMA).
Fig 2
Fig 2. Field area of included articles.
Fig 3
Fig 3. Publication types of included articles.
See this image and copyright information in PMC

References

    1. Chen MH, Leow A, Ross MK, DeLuca J, Chiaravalloti N, Costa SL, et al.. Associations between smartphone keystroke dynamics and cognition in MS. DIGITAL HEALTH. 2022;8: 205520762211432. doi: 10.1177/20552076221143234 - DOI - PMC - PubMed
    1. Verghese J, Robbins M, Holtzer R, Zimmerman M, Wang C, Xue X, et al.. Gait Dysfunction in Mild Cognitive Impairment Syndromes. J American Geriatrics Society. 2008;56: 1244–1251. doi: 10.1111/j.1532-5415.2008.01758.x - DOI - PMC - PubMed
    1. Strimbu K, Tavel JA. What are biomarkers?: Current Opinion in HIV and AIDS. 2010;5: 463–466. doi: 10.1097/COH.0b013e32833ed177 - DOI - PMC - PubMed
    1. Conn CW, Jin J. The value of companion diagnostics in oncology drug development. Expert Review of Molecular Diagnostics. 2022;22: 591–593. doi: 10.1080/14737159.2022.2100697 - DOI - PubMed
    1. Jørgensen JT, Winther H, Askaa J, Andresen L, Olsen D, Mollerup J. A Companion Diagnostic With Significant Clinical Impact in Treatment of Breast and Gastric Cancer. Front Oncol. 2021;11: 676939. doi: 10.3389/fonc.2021.676939 - DOI - PMC - PubMed

Publication types

LinkOut - more resources