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Review
. 2024 May-Jun;30(3):202-209.
doi: 10.1097/PPO.0000000000000717.

Bone Metastases

Gary J R Cook  1 , Matthew P Thorpe  2
Affiliations
Review

Bone Metastases

Gary J R Cook et al. Cancer J. 2024 May-Jun.

Abstract

Bone metastases occur frequently in common malignancies such as breast and prostate cancer. They are responsible for considerable morbidity and skeletal-related events. Fortunately, there are now several systemic, focal, and targeted therapies that can improve quality and length of life, including radionuclide therapies. It is therefore important that bone metastases can be detected as early as possible and that treatment can be accurately and sensitively monitored. Several bone-specific and tumor-specific single-photon emission computed tomography and positron emission tomography molecular imaging agents are available, for detection and monitoring response to systemic therapeutics, as well as theranostic agents to confirm target expression and predict response to radionuclide therapies.

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Conflict of interest statement

Conflicts of Interest and Sources of Funding: The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article.

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