Antimicrobial susceptibility of Pneumocystis carinii in culture
- PMID: 3875445
- DOI: 10.1016/0732-8893(85)90076-8
Antimicrobial susceptibility of Pneumocystis carinii in culture
Abstract
Pneumocystis carinii from infected rats were cultured on infected WI-38 human lung fibroblasts. After cultures were established, medium was replaced by medium containing antimicrobials and supernate organisms counted at specified times. Results show that metronidazole had no effect, amphotericin B suppressed organisms at 5 but not 0.5 microgram/ml, and miconazole, chloroquine, trimethoprim-sulfamethoxazole, and pentamidine isethionate suppressed organisms at the concentrations tested.
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