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Comparative Study
. 1985 Sep;3(5):381-7.
doi: 10.1016/0732-8893(85)90076-8.

Antimicrobial susceptibility of Pneumocystis carinii in culture

Comparative Study

Antimicrobial susceptibility of Pneumocystis carinii in culture

M S Bartlett et al. Diagn Microbiol Infect Dis. 1985 Sep.

Abstract

Pneumocystis carinii from infected rats were cultured on infected WI-38 human lung fibroblasts. After cultures were established, medium was replaced by medium containing antimicrobials and supernate organisms counted at specified times. Results show that metronidazole had no effect, amphotericin B suppressed organisms at 5 but not 0.5 microgram/ml, and miconazole, chloroquine, trimethoprim-sulfamethoxazole, and pentamidine isethionate suppressed organisms at the concentrations tested.

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