Non-Small Cell Lung Cancer, Version 4.2024, NCCN Clinical Practice Guidelines in Oncology

doi:10.6004/jnccn.2204.0023

Practice Guideline

. 2024 May;22(4):249-274.

doi: 10.6004/jnccn.2204.0023.

Non-Small Cell Lung Cancer, Version 4.2024, NCCN Clinical Practice Guidelines in Oncology

Gregory J Riely¹, Douglas E Wood², David S Ettinger³, Dara L Aisner⁴, Wallace Akerley⁵, Jessica R Bauman⁶, Ankit Bharat⁷, Debora S Bruno⁸, Joe Y Chang⁹, Lucian R Chirieac¹⁰, Malcolm DeCamp¹¹, Aakash P Desai¹², Thomas J Dilling¹³, Jonathan Dowell¹⁴, Gregory A Durm¹⁵, Scott Gettinger¹⁶, Travis E Grotz¹⁷, Matthew A Gubens¹⁸, Aditya Juloori¹⁹, Rudy P Lackner²⁰, Michael Lanuti²¹, Jules Lin²², Billy W Loo²³, Christine M Lovly²⁴, Fabien Maldonado²⁴, Erminia Massarelli²⁵, Daniel Morgensztern²⁶, Trey C Mullikin²⁷, Thomas Ng²⁸, Dawn Owen¹⁷, Dwight H Owen²⁹, Sandip P Patel³⁰, Tejas Patil⁴, Patricio M Polanco¹⁴, Jonathan Riess³¹, Theresa A Shapiro³, Aditi P Singh³², James Stevenson⁸, Alda Tam⁹, Tawee Tanvetyanon¹³, Jane Yanagawa³³, Stephen C Yang³, Edwin Yau³⁴, Kristina M Gregory³⁵, Lisa Hang³⁵

Affiliations

¹ 1Memorial Sloan Kettering Cancer Center.
² 2Fred Hutchinson Cancer Center.
³ 3The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
⁴ 4University of Colorado Cancer Center.
⁵ 5Huntsman Cancer Institute at the University of Utah.
⁶ 6Fox Chase Cancer Center.
⁷ 7Robert H. Lurie Comprehensive Cancer Center of Northwestern University.
⁸ 8Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute.
⁹ 9The University of Texas MD Anderson Cancer Center.
¹⁰ 10Dana-Farber/Brigham and Women's Cancer Center.
¹¹ 11University of Wisconsin Carbone Cancer Center.
¹² 12O'Neal Comprehensive Cancer Center at UAB.
¹³ 13Moffitt Cancer Center.
¹⁴ 14UT Southwestern Simmons Comprehensive Cancer Center.
¹⁵ 15Indiana University Melvin and Bren Simon Comprehensive Cancer Center.
¹⁶ 16Yale Cancer Center/Smilow Cancer Hospital.
¹⁷ 17Mayo Clinic Comprehensive Cancer Center.
¹⁸ 18UCSF Helen Diller Family Comprehensive Cancer Center.
¹⁹ 19The UChicago Medicine Comprehensive Cancer Center.
²⁰ 20Fred & Pamela Buffett Cancer Center.
²¹ 21Mass General Cancer Center.
²² 22University of Michigan Rogel Cancer Center.
²³ 23Stanford Cancer Institute.
²⁴ 24Vanderbilt-Ingram Cancer Center.
²⁵ 25City of Hope National Medical Center.
²⁶ 26Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine.
²⁷ 27Duke Cancer Institute.
²⁸ 28The University of Tennessee Health Science Center.
²⁹ 29The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.
³⁰ 30UC San Diego Moores Cancer Center.
³¹ 31UC Davis Comprehensive Cancer Center.
³² 32Abramson Cancer Center at the University of Pennsylvania.
³³ 33UCLA Jonsson Comprehensive Cancer Center.
³⁴ 34Roswell Park Comprehensive Cancer Center.
³⁵ 35National Comprehensive Cancer Network.

PMID: 38754467
DOI: 10.6004/jnccn.2204.0023

Practice Guideline

Non-Small Cell Lung Cancer, Version 4.2024, NCCN Clinical Practice Guidelines in Oncology

Gregory J Riely et al. J Natl Compr Canc Netw. 2024 May.

. 2024 May;22(4):249-274.

doi: 10.6004/jnccn.2204.0023.

Authors

Affiliations

¹ 1Memorial Sloan Kettering Cancer Center.
² 2Fred Hutchinson Cancer Center.
³ 3The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
⁴ 4University of Colorado Cancer Center.
⁵ 5Huntsman Cancer Institute at the University of Utah.
⁶ 6Fox Chase Cancer Center.
⁷ 7Robert H. Lurie Comprehensive Cancer Center of Northwestern University.
⁸ 8Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute.
⁹ 9The University of Texas MD Anderson Cancer Center.
¹⁰ 10Dana-Farber/Brigham and Women's Cancer Center.
¹¹ 11University of Wisconsin Carbone Cancer Center.
¹² 12O'Neal Comprehensive Cancer Center at UAB.
¹³ 13Moffitt Cancer Center.
¹⁴ 14UT Southwestern Simmons Comprehensive Cancer Center.
¹⁵ 15Indiana University Melvin and Bren Simon Comprehensive Cancer Center.
¹⁶ 16Yale Cancer Center/Smilow Cancer Hospital.
¹⁷ 17Mayo Clinic Comprehensive Cancer Center.
¹⁸ 18UCSF Helen Diller Family Comprehensive Cancer Center.
¹⁹ 19The UChicago Medicine Comprehensive Cancer Center.
²⁰ 20Fred & Pamela Buffett Cancer Center.
²¹ 21Mass General Cancer Center.
²² 22University of Michigan Rogel Cancer Center.
²³ 23Stanford Cancer Institute.
²⁴ 24Vanderbilt-Ingram Cancer Center.
²⁵ 25City of Hope National Medical Center.
²⁶ 26Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine.
²⁷ 27Duke Cancer Institute.
²⁸ 28The University of Tennessee Health Science Center.
²⁹ 29The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.
³⁰ 30UC San Diego Moores Cancer Center.
³¹ 31UC Davis Comprehensive Cancer Center.
³² 32Abramson Cancer Center at the University of Pennsylvania.
³³ 33UCLA Jonsson Comprehensive Cancer Center.
³⁴ 34Roswell Park Comprehensive Cancer Center.
³⁵ 35National Comprehensive Cancer Network.

PMID: 38754467
DOI: 10.6004/jnccn.2204.0023

Abstract

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Non-Small Cell Lung Cancer (NSCLC) provide recommendations for the treatment of patients with NSCLC, including diagnosis, primary disease management, surveillance for relapse, and subsequent treatment. The panel has updated the list of recommended targeted therapies based on recent FDA approvals and clinical data. This selection from the NCCN Guidelines for NSCLC focuses on treatment recommendations for advanced or metastatic NSCLC with actionable molecular biomarkers.

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Update of

Non-Small Cell Lung Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology.
Ettinger DS, Wood DE, Aisner DL, Akerley W, Bauman JR, Bharat A, Bruno DS, Chang JY, Chirieac LR, D'Amico TA, DeCamp M, Dilling TJ, Dowell J, Gettinger S, Grotz TE, Gubens MA, Hegde A, Lackner RP, Lanuti M, Lin J, Loo BW, Lovly CM, Maldonado F, Massarelli E, Morgensztern D, Ng T, Otterson GA, Pacheco JM, Patel SP, Riely GJ, Riess J, Schild SE, Shapiro TA, Singh AP, Stevenson J, Tam A, Tanvetyanon T, Yanagawa J, Yang SC, Yau E, Gregory K, Hughes M. Ettinger DS, et al. J Natl Compr Canc Netw. 2022 May;20(5):497-530. doi: 10.6004/jnccn.2022.0025. J Natl Compr Canc Netw. 2022. Update in: J Natl Compr Canc Netw. 2024 May;22(4):249-274. doi: 10.6004/jnccn.2204.0023. PMID: 35545176 Updated.

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Non-Small Cell Lung Cancer, Version 4.2024, NCCN Clinical Practice Guidelines in Oncology

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Non-Small Cell Lung Cancer, Version 4.2024, NCCN Clinical Practice Guidelines in Oncology

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