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Review
. 2024 Jun;71(3):529-549.
doi: 10.1016/j.pcl.2024.01.018. Epub 2024 Mar 12.

Vaccine Development

Elizabeth A D Hammershaimb  1 , James D Campbell  2
Affiliations
Review

Vaccine Development

Elizabeth A D Hammershaimb et al. Pediatr Clin North Am. 2024 Jun.

Abstract

This article considers ethical considerations surrounding pediatric vaccine development for pandemic preparedness, examines some historical cases of pediatric vaccines developed during past smallpox, influenza, and 2019 coronavirus disease pandemics, and discusses the current state of vaccine development for pandemic preparedness, including vaccines against smallpox/mpox, influenza, anthrax, and Ebola that are included in the US Strategic National Stockpile and vaccines being developed against priority pathogens identified by the World Health Organization.

Keywords: Anthrax; COVID-19; Ebola; Emerging infections; Influenza; Mpox; Pediatric vaccines; Smallpox.

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Conflict of interest statement

Disclosures E.A. Hammershaimb and J.D. Campbell are investigators on clinical trials of COVID-19 vaccines developed by Moderna and Novavax and of an anthrax vaccine developed by Emergent. Their institution receives funds for the conduct of these trials; the authors have no direct financial interests in any of these companies.