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. 1985;22(2):123-30.
doi: 10.1007/BF00563509.

An Ia-positive mouse T-cell clone is functional in presenting antigen to other T cells

A Ben-Nun, W Strauss, S A Leeman, L E Cohn, C Murre, A Duby, J G Seidman, L H Glimcher

An Ia-positive mouse T-cell clone is functional in presenting antigen to other T cells

A Ben-Nun et al. Immunogenetics. 1985.

Abstract

In this report we present data demonstrating the endogenous expression of I-region associated (Ia) antigens on a cloned line of mouse T cells, CTLL, as well as transcription of the invariant chain gene in these cells. We demonstrate further that this Ia-bearing T-cell clone, CTLL, can utilize the expressed Ia molecules to present antigen to Ia-restricted antigen-specific T cells.

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