Gigantic laryngeal schwannoma: A case report with literature review

Abstract

Laryngeal schwannoma is a rare benign nerve sheath tumor that is slow growing. The diagnosis is made from a combination of clinical, radiological, and histopathological findings, and the main method of treatment is resection. We report a case of a 69-year-old presenting with a neck mass causing stridor, dysphagia, and orthopnea. CT of the neck showed an enhancing mass measuring 6.3 cm and extending superior to the larynx. Emergent tracheostomy and mass resection were performed, and histopathology and immunohistochemical findings were obtained from the specimen supporting schwannoma. In conclusion, while rare, schwannoma should always be considered as a differential diagnosis for a laryngeal mass. More studies are needed to assess the size and prognosis of the tumor.

Keywords: Schwannoma; immunohistochemistry; larynx; nerve sheath tumor; pathology.

Figure 1.

CT Soft Tissue of Neck to Show a Heterogeneous Enhancing Mass Measuring 6.3 x 5.8 x 4.1 cm (arrow pointed to the tumor).

Figure 2.

Microscopical And Immunohistochemical Profile of The Tumor; (A): Fibrous Capsule with Antoni B Pattern Area (10X); (B): Antoni A Pattern and Verocay Bodies (10X); (C): S100, strong and diffuse (10X); (D): SOX10, strong and diffuse (10X); (E): CD34, highlight on blood vessels (10X); (F): Ki-67, minimal less than 1% (10X).