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Case Reports
. 2024 Aug;48(4):2583-2588.
doi: 10.1007/s11259-024-10413-0. Epub 2024 May 17.

An atypical case of chronic paracoccidioidomycosis in a dog caused by a fungus from the Paracoccidioides brasiliensis complex

Igor Massahiro de Souza Suguiura  1   2 , Felipe Martins Negreiros Navolar  3 , Bruna Alves Souza  4 , Mariana Lopes Silvestre Simioni  4 , Giovana Gomes de Carvalho Ishiuchi  5 , Rafaela Macagnan  6 , Eiko Nakagawa Itano  7 , Ayako Sano  8 , Ana Paula Frederico Loureiro Bracarense  3 , Mario Augusto Ono  5
Affiliations
Case Reports

An atypical case of chronic paracoccidioidomycosis in a dog caused by a fungus from the Paracoccidioides brasiliensis complex

Igor Massahiro de Souza Suguiura et al. Vet Res Commun. 2024 Aug.

Abstract

Paracoccidioidomycosis (PCM) is a systemic mycosis endemic in Latin American countries and one of the most important fungal diseases regarding incidence and mortality in humans. PCM has also been described in some animal species such as dogs. In this study we describe a new case of PCM disease in a dog that differed from previous records in the literature which includes a progressive evolution of fungal dermatitis causing a deforming lesion in the nose, like those found in human patients, and humoral response against gp70 instead of gp43, the major diagnostic antigen for human PCM. The clinical isolate through the ITS and partial gp43 gene phylogenetic analysis was grouped in the Paracoccidioides brasiliensis complex. This case describes several features which may contribute to improving diagnosis and understanding of canine paracoccidioidomycosis.

Keywords: Animals; Diagnosis; LAMP; Mycosis; Serology; Veterinary.

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