A practical guide to data management and sharing for biomedical laboratory researchers
- PMID: 38762093
- DOI: 10.1016/j.expneurol.2024.114815
A practical guide to data management and sharing for biomedical laboratory researchers
Abstract
Effective data management and sharing have become increasingly crucial in biomedical research; however, many laboratory researchers lack the necessary tools and knowledge to address this challenge. This article provides an introductory guide into research data management (RDM), and the importance of FAIR (Findable, Accessible, Interoperable, and Reusable) data-sharing principles for laboratory researchers produced by practicing scientists. We explore the advantages of implementing organized data management strategies and introduce key concepts such as data standards, data documentation, and the distinction between machine and human-readable data formats. Furthermore, we offer practical guidance for creating a data management plan and establishing efficient data workflows within the laboratory setting, suitable for labs of all sizes. This includes an examination of requirements analysis, the development of a data dictionary for routine data elements, the implementation of unique subject identifiers, and the formulation of standard operating procedures (SOPs) for seamless data flow. To aid researchers in implementing these practices, we present a simple organizational system as an illustrative example, which can be tailored to suit individual needs and research requirements. By presenting a user-friendly approach, this guide serves as an introduction to the field of RDM and offers practical tips to help researchers effortlessly meet the common data management and sharing mandates rapidly becoming prevalent in biomedical research.
Keywords: Data sharing; Research data management.
Copyright © 2024. Published by Elsevier Inc.
Conflict of interest statement
Declaration of competing interest ARF: Consulting: Santa Clara Valley Medical Center (Biostats Consultant), Neuronasal Inc. (SAB), SpineX Inc. (DSMB), Industry Collaboration (non-financial): DataRobot: AI for Good program. MEM and JG: Co-creator of SciCrunch, a platform to create data and resource sharing communities. ATE: co-owner of YEG scientific, a company producing behavioral research tools for animal models of disease. All other authors have nothing to declare.
Similar articles
-
Setting up an institutional OMERO environment for bioimage data: Perspectives from both facility staff and users.J Microsc. 2025 Jan;297(1):105-119. doi: 10.1111/jmi.13360. Epub 2024 Sep 14. J Microsc. 2025. PMID: 39275979 Free PMC article.
-
Data management and sharing.J Clin Epidemiol. 2025 Apr;180:111680. doi: 10.1016/j.jclinepi.2025.111680. Epub 2025 Jan 20. J Clin Epidemiol. 2025. PMID: 39842522
-
Digitalization of biocatalysis: Best practices to research data management.Methods Enzymol. 2025;714:19-43. doi: 10.1016/bs.mie.2025.01.040. Epub 2025 Feb 13. Methods Enzymol. 2025. PMID: 40288838
-
FAIR SCI Ahead: The Evolution of the Open Data Commons for Pre-Clinical Spinal Cord Injury Research.J Neurotrauma. 2020 Mar 15;37(6):831-838. doi: 10.1089/neu.2019.6674. Epub 2019 Dec 6. J Neurotrauma. 2020. PMID: 31608767 Free PMC article. Review.
-
The challenges of research data management in cardiovascular science: a DGK and DZHK position paper-executive summary.Clin Res Cardiol. 2024 May;113(5):672-679. doi: 10.1007/s00392-023-02303-3. Epub 2023 Oct 17. Clin Res Cardiol. 2024. PMID: 37847314 Free PMC article. Review.
Cited by
-
The past, present and future of neuroscience data sharing: a perspective on the state of practices and infrastructure for FAIR.Front Neuroinform. 2024 Jan 5;17:1276407. doi: 10.3389/fninf.2023.1276407. eCollection 2023. Front Neuroinform. 2024. PMID: 38250019 Free PMC article. Review.
-
A how-to guide for code sharing in biology.PLoS Biol. 2024 Sep 10;22(9):e3002815. doi: 10.1371/journal.pbio.3002815. eCollection 2024 Sep. PLoS Biol. 2024. PMID: 39255324 Free PMC article. Review.
-
A natural language processing approach to support biomedical data harmonization: Leveraging large language models.PLoS One. 2025 Jul 24;20(7):e0328262. doi: 10.1371/journal.pone.0328262. eCollection 2025. PLoS One. 2025. PMID: 40705832 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources