Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2024 May 3:14:1363055.
doi: 10.3389/fonc.2024.1363055. eCollection 2024.

Recurrent retroperitoneal liposarcoma with multiple surgeries: a case report

Xiao Wang  1   2 , Xiaobiao Song  1 , Qiang Song  1 , Jijun Wang  1 , Junsheng Chen  1
Affiliations
Case Reports

Recurrent retroperitoneal liposarcoma with multiple surgeries: a case report

Xiao Wang et al. Front Oncol. .

Abstract

Retroperitoneal liposarcoma (RPLPS) is a rare malignant tumor that is typically treated with surgical resection. However, RPLPS often has a high rate of local recurrence, making it crucial to explore new treatment options. In this report, we present the case of a middle-aged woman who experienced seven recurrences and underwent seven surgeries following the initial resection. Currently, the patient's condition remains stable after the eighth surgery. Although there have been numerous reports of RPLPS cases both domestically and internationally, instances of repeated recurrence like this are exceptionally rare. Therefore, we have gathered the patient's case data and conducted a retrospective analysis, incorporating relevant literature, to enhance the understanding of this disease among clinical practitioners.

Keywords: auxiliary treatment; case report; recurrence; retroperitoneal liposarcoma; surgical treatment.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
(A–D) Abdominal CT showed multiple huge masses in the abdominal cavity. By the eighth surgery, the larger masses had grown to 23×12 cm.
Figure 2
Figure 2
(A, B) Frontal and lateral appearance of the patient’s abdomen before the eighth surgery. (C) A total of 21 retroperitoneal tumors were removed in the eighth operation. (D, E) The maximum size of the tumor is 32×26cm, and the cut surface is fish-shaped.
Figure 3
Figure 3
The patient’s eighth postoperative pathological analysis (hematoxylin and eosin staining, ×100 magnification) showed dedifferentiated liposarcoma, with localized pleomorphic liposarcoma.
Figure 4
Figure 4
Timeline of this case.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Rachman Y, Hardja Y. Giant retroperitoneal liposarcoma: A case report. Int J Surg Case Rep. (2022) 97:107465. doi: 10.1016/j.ijscr.2022.107465 - DOI - PMC - PubMed
    1. Choi JH, Ro JY. The 2020 WHO classification of tumors of soft tissue: selected changes and new entities. Adv Anat Pathol. (2021) 28:44–58. doi: 10.1097/PAP.0000000000000284 - DOI - PubMed
    1. Xiao J, Liu J, Chen M, Liu W, He X. Diagnosis and prognosis of retroperitoneal liposarcoma: A single Asian center cohort of 57 cases. J Oncol. (2021) 2021:7594027. doi: 10.1155/2021/7594027 - DOI - PMC - PubMed
    1. Suryabanshi A, Timilsina B, Khadka N, Rijal A, Bhandari RS. Huge retroperitoneal liposarcoma encasing right kidney: A case report from Nepal. Int J Surg Case Rep. (2022) 99:107647. doi: 10.1016/j.ijscr.2022.107647 - DOI - PMC - PubMed
    1. Mansour S, Azzam N, Kluger Y, Khuri S. Retroperitoneal liposarcoma: the giant type. J Med cases. (2022) 13:517–20. doi: 10.14740/jmc4014 - DOI - PMC - PubMed

Publication types

LinkOut - more resources