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Editorial
. 2024 Aug;99(8):1459-1461.
doi: 10.1002/ajh.27375. Epub 2024 May 20.

Treatment-associated decline in JAK2V617F allele burden in polycythemia vera: What does it mean?

Ayalew Tefferi  1 , Animesh Pardanani  1 , Naseema Gangat  1
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Free article
Editorial

Treatment-associated decline in JAK2V617F allele burden in polycythemia vera: What does it mean?

Ayalew Tefferi et al. Am J Hematol. 2024 Aug.
Free article
No abstract available

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References

REFERENCES

    1. James C, Ugo V, Le Couedic JP, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature. 2005;434:1144‐1148.
    1. Klampfl T, Gisslinger H, Harutyunyan AS, et al. Somatic mutations of calreticulin in myeloproliferative neoplasms. N Engl J Med. 2013;369:2379‐2390.
    1. Chachoua I, Pecquet C, El‐Khoury M, et al. Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants. Blood. 2016;127:1325‐1335.
    1. Pikman Y, Lee BH, Mercher T, et al. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. PLoS Med. 2006;3:e270.
    1. Tefferi A, Pardanani A, Gangat N. Momelotinib expands the therapeutic armamentarium for myelofibrosis: impact on hierarchy of treatment choices. Am J Hematol. 2024;99:300‐308.

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