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. 2024 Aug 1;110(8):4624-4632.
doi: 10.1097/JS9.0000000000001560.

Association between daily sitting time and kidney stones based on the National Health and Nutrition Examination Survey (NHANES) 2007-2016: a cross-sectional study

Ya Li  1 , Xingpeng Di, Mengzhu Liu, Jingwen Wei, Tianyue Li, Banghua Liao
Affiliations

Association between daily sitting time and kidney stones based on the National Health and Nutrition Examination Survey (NHANES) 2007-2016: a cross-sectional study

Ya Li et al. Int J Surg. .

Abstract

Background: Kidney stones are among the most common urological conditions affecting ~9% of the world population. Although some unhealthy diets and unhealthy lifestyles are reportedly risk factors for kidney stone, the association between daily sitting time and kidney stone has not been explored.

Materials and methods: This large-scale, cross-sectional study was conducted using data from the National Health and Nutrition Examination Survey (NHANES) database 2007-2016. Kidney stone history and daily sitting time were retrieved from the questionnaire and 24 hour (h) recall interviews. Logistic regression and subgroup analysis were conducted to investigate the association. The analysis was further stratified by vigorous recreational activity.

Results: A total of 19 188 participants aged ≥20 years with complete information were included in this study. The overall prevalence of kidney stone was 9.6%. Among participants without vigorous recreational activity, a trend towards an increasing prevalence of kidney stone was observed with increased daily sitting time. However, the trend was not observed in individuals who participated in vigorous recreational activity, as they experienced a decreased risk of kidney stone despite having a daily sitting time of 6-8 h (crude model OR=0.659, 95% CI: 0.457-0.950, P =0.028), indicating that vigorous recreational activity may partially attenuate the detrimental effect of prolonged sitting time.

Conclusion: Our study revealed an increasing trend of prevalence of kidney stone with increased daily sitting time among the population not performing vigorous recreational activity despite the difference was nonsignificant. Vigorous recreational activity may modify the association between daily sitting time and kidney stone. More prospective cohort studies are warranted to further examine this association.

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Conflict of interest statement

We declare that there are no conflicts of interests.

Figures

Figure 1
Figure 1
Flow diagram of participant screening. NHANES, National Health and Nutrition Examination Survey.
Figure 2
Figure 2
Adjusted prevalence of kidney stone among participants with different daily sitting time. Red indicates participants without vigorous activity. Blue indicates participants with vigorous activity.
See this image and copyright information in PMC

References

    1. Scales CD, Jr, Smith AC, Hanley JM, et al. . Prevalence of kidney stones in the United States. Eur Urol 2012;62:160–165. - PMC - PubMed
    1. Antonelli JA, Maalouf NM, Pearle MS, et al. . Use of the National Health and Nutrition Examination Survey to calculate the impact of obesity and diabetes on cost and prevalence of urolithiasis in 2030. Eur Urol 2014;66:724–729. - PMC - PubMed
    1. Zeng G, Mai Z, Xia S, et al. . Prevalence of kidney stones in China: an ultrasonography based cross-sectional study. BJU Int 2017;120:109–116. - PubMed
    1. Yasui T, Okada A, Hamamoto S, et al. . Pathophysiology-based treatment of urolithiasis. Int J Urol 2017;24:32–38. - PubMed
    1. Sasmaz M, Kirpat V. The relationship between the severity of pain and stone size, hydronephrosis and laboratory parameters in renal colic attack. Am J Emerg Med 2019;37:2107–2110. - PubMed

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